中国动态血糖监测临床应用指南(2016年版)

2016-11-20 董天娇 心血管时间

在中华医学会糖尿病学分会第二十次全国学术会议(CDS2016)上,天津医科大学代谢病医院陈莉明教授介绍了中国动态血糖监测临床应用指南(2016 年版)。血糖监测是糖尿病管理中的重要组成部分,血糖监测的结果有助于评估糖尿病患者糖代谢紊乱的程度和制定降糖方案。近年,动态血糖监测(CGM)领域发展迅速,2016 年美国临床内分泌医师学会(AACE)与美国内分泌学会(ACE)发表了《动态血糖监测临床应用共

在中华医学会糖尿病学分会第二十次全国学术会议(CDS2016)上,天津医科大学代谢病医院陈莉明教授介绍了中国动态血糖监测临床应用指南(2016 年版)。


血糖监测是糖尿病管理中的重要组成部分,血糖监测的结果有助于评估糖尿病患者糖代谢紊乱的程度和制定降糖方案。近年,动态血糖监测(CGM)领域发展迅速,2016 年美国临床内分泌医师学会(AACE)与美国内分泌学会(ACE)发表了《动态血糖监测临床应用共识》。


我国 CGM 相关临床应用及研究也取得较大进展,发表了许多具有借鉴意义的研究成果,为修订指南提供了第一手资料。中华医学会糖尿病学分会再次修订《中国动态血糖监测临床应用指南》,以适应血糖监测发展趋势。 


CGM 可以了解血糖波动的趋势,发现不易被传统监测方法所检测到的高血糖和低血糖。因此,CGM 可成为传统血糖监测方法的有效补充。CGM 技术分为回顾性 CGM(retrospective CGM)和实时 CGM(real-time CGM)两种。回顾性 CGM 通过植入皮下感应器 24 h 连续监测葡萄糖水平,连续显示血糖随饮食、药物、运动等事件的变化,可以了解患者血糖变化的整体趋势和个体化特征。


回顾性 CGM 主要适用于:


1. 1 型糖尿病。

2. 需要胰岛素强化治疗的 2 型糖尿病患者。

3. 在 SMBG 的指导下给予降糖治疗的 2 型糖尿病患者,仍出现无法解释的严重低血糖或反复低血糖、无症状性低血糖、夜间低血糖。

4. 无法解释的高血糖,特别是空腹高血糖,血糖波动大。

5. 出于对低血糖的恐惧,刻意保持高血糖状态的患者。

6. 妊娠期糖尿病或糖尿病合并妊娠。患者教育中 CGM 可以帮助患者了解运动、饮食、应激、降糖治疗等导致的血糖变化,促进医患双方更有效的沟通。


实时 CGM 是在提供即时血糖信息的同时提供高、低血糖报警、预警功能,协助患者进行即时血糖调节。有循证医学证据表明在实时 CGM 指导下进行血糖管理,可以达到更优质的降糖效果,且糖化血红蛋白的下降与监测探头的使用频率呈正相关。与回顾性 CGM 技术相比,实时 CGM 技术的临床定位和患者的获益有所不同。


目前推荐的适应证为:


1. HbA1c<7% 的儿童和青少年 1 型糖尿病患者,使用实时 CGM 可辅助患者 HbA1c 水平持续达标,且不增加低血糖发生风险。

2. HbA1c>7% 的儿童和青少年 1 型糖尿病患者,如有能力每日使用和操作仪器。

3. 有能力接近每日使用的成人 1 型糖尿病患者。

4. 住院胰岛素治疗的 2 型糖尿病患者,使用实时 CGM 可以减少血糖波动,使血糖更快、更平稳达标,同时不增加低血糖风险。

5. 围手术期 2 型糖尿病患者。

6. 非重症监护室使用胰岛素治疗的患者,应用实时 CGM 有助于血糖控制并减少低血糖的发生。

7. 此外,中国动态血糖监测临床应用指南(2016 版)完善了实时 CGM 技术的临床应用,实时 CGM 技术的使用规范和实时 CGM 技术在患者教育中应用等内容。

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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-12-06 脱因不花

    大补,我还一直停留在2012版的

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Nov 23 12:53:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540181, encodeId=e9bf1540181df, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Tue Nov 22 13:46:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157213, encodeId=0d0915e213b0, content=不错的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:25 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157212, encodeId=b80115e212f9, content=跟老师们学习,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:16 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157173, encodeId=cdf015e173d0, content=有据可依,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-12-03 Tulipzyz

    动态,厉害

    0

  5. 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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-28 小试牛刀

    非常好,还没有看。

    0

  6. 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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-23 虈亣靌

    讲得好分享了

    0

  7. 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createdBy=142f29025688, createdName=wgsun, createdTime=Thu Jun 08 21:46:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160706, encodeId=f15c160e06aa, content=大补,我还一直停留在2012版的, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/AVuQQYjiarbnOmL25xBrlibxxMYoiaCUNwvQ4Z6nwF9aUejcxflFtKgxazNay1EDkYc1ITibjVbjQDhIHBUT2VFQ4g/0, createdBy=47661980738, createdName=脱因不花, createdTime=Tue Dec 06 15:25:17 CST 2016, time=2016-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160026, encodeId=22e6160026f7, content=动态,厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef621732290, createdName=Tulipzyz, createdTime=Sat Dec 03 23:47:39 CST 2016, time=2016-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=158669, encodeId=a3cb1586698a, content=非常好,还没有看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161123/IMG58353EBDBBB8A8627.jpg, createdBy=64bf1984729, createdName=小试牛刀, createdTime=Mon Nov 28 10:36:34 CST 2016, time=2016-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157621, encodeId=170515e62140, content=讲得好分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Nov 23 12:53:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540181, encodeId=e9bf1540181df, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Tue Nov 22 13:46:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157213, encodeId=0d0915e213b0, content=不错的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:25 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157212, encodeId=b80115e212f9, content=跟老师们学习,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:16 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157173, encodeId=cdf015e173d0, content=有据可依,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1835660, encodeId=a4d71835660d5, content=<a href='/topic/show?id=cfdc22e893f' target=_blank style='color:#2F92EE;'>#临床应用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22789, encryptionId=cfdc22e893f, topicName=临床应用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Thu Feb 16 12:46:00 CST 2017, time=2017-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1690307, encodeId=c033169030e44, content=<a href='/topic/show?id=2c33331223f' target=_blank style='color:#2F92EE;'>#动态血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33122, encryptionId=2c33331223f, topicName=动态血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Nov 23 12:53:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540181, encodeId=e9bf1540181df, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Tue Nov 22 13:46:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157213, encodeId=0d0915e213b0, content=不错的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, 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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 1771ae4158m

    不错的文章

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Nov 23 12:53:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540181, encodeId=e9bf1540181df, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Tue Nov 22 13:46:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157213, encodeId=0d0915e213b0, content=不错的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:25 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157212, encodeId=b80115e212f9, content=跟老师们学习,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:16 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157173, encodeId=cdf015e173d0, content=有据可依,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 1771ae4158m

    跟老师们学习,好

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Nov 23 12:53:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540181, encodeId=e9bf1540181df, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Tue Nov 22 13:46:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157213, encodeId=0d0915e213b0, content=不错的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:25 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157212, encodeId=b80115e212f9, content=跟老师们学习,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Nov 21 08:44:16 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157173, encodeId=cdf015e173d0, content=有据可依,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 06:58:43 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 susice

    有据可依,挺好

    0