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实验性反义寡核苷酸GTX-102治疗Angelman综合征的临床试验即将开始

2020-02-15 Allan MedSci原创

GTX-102反义寡核苷酸Angelman综合征天使人综合征
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生物制药公司GeneTx今日宣布，将开始进行GTX-102治疗Angelman综合征的临床试验，GTX-102是一种实验性反义寡核苷酸药物，正在评估其对Angelman综合征（AS）的安全性和耐受性。

生物制药公司GeneTx今日宣布，将开始进行GTX-102治疗Angelman综合征的临床试验，GTX-102是一种实验性反义寡核苷酸药物，正在评估其对Angelman综合征（AS）的安全性和耐受性。这项I/II期开放标签、多剂量研究的目的是评估GTX-102治疗Angelman综合征患儿的安全性、耐受性以及血浆和脑脊液（CSF）浓度。将招募大约20名患儿，这些患者经遗传学确诊为母体UBE3A基因完全缺失。

Angelman综合征（天使人综合征）是一种基因缺陷而造成的疾病。罹患此症的儿童，脸上常有笑容，缺乏语言能力、过动，且智能低下。患者中约80%会有癫痫症状、约50%患有小头症。Angelman综合征的病因是由于来自母亲的第15号染色体印迹基因区15q部分缺陷，或同时拥有两条来自父亲的带有此缺陷的第15号染色体。


原始出处：

https://www.firstwordpharma.com/node/1700982

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    2020-08-30 zzc2211

    #GTX-102#

    0

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    2020-05-01 xsm918

    #核苷酸#

    0

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    2020-11-02 mjldent

    #Angelman综合征#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1968141, encodeId=6e9e196814191, content=<a href='/topic/show?id=f233831582' target=_blank style='color:#2F92EE;'>#GTX-102#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8315, encryptionId=f233831582, topicName=GTX-102)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Sun Aug 30 04:45:00 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945646, encodeId=b185194564602, content=<a href='/topic/show?id=a9fa62150e8' target=_blank style='color:#2F92EE;'>#核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62150, encryptionId=a9fa62150e8, topicName=核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49cf452, createdName=xsm918, createdTime=Fri May 01 06:45:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989500, encodeId=5cef198950068, content=<a href='/topic/show?id=941d251492' target=_blank style='color:#2F92EE;'>#Angelman综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2514, encryptionId=941d251492, topicName=Angelman综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Nov 02 04:45:00 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040761, encodeId=f2f22040e61ab, content=<a href='/topic/show?id=5887461103d' target=_blank style='color:#2F92EE;'>#实验性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46110, encryptionId=5887461103d, topicName=实验性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Jul 20 13:45:00 CST 2020, time=2020-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700420, encodeId=f6361e0042040, content=<a href='/topic/show?id=2f93465966d' target=_blank style='color:#2F92EE;'>#寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46596, encryptionId=2f93465966d, topicName=寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=491a30091205, createdName=DEXTER3149, createdTime=Sat Jan 09 23:45:00 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431757, encodeId=4e6d1431e5790, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575373, encodeId=9a0f15e537311, content=<a href='/topic/show?id=03753e66414' target=_blank style='color:#2F92EE;'>#反义寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37664, encryptionId=03753e66414, topicName=反义寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfc816121587, createdName=fyxzlh, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=379288, encodeId=2bcb3e928847, content=学习中学习中谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJm4xPKAf4u6XWj35VVrjsS7zV0iceXLnUFyPcpCEs1Zws5knTcAxG7qOtflUuDHnbmVwUSbawnTUw/132, createdBy=4bea5277230, createdName=lian6388, createdTime=Sat Feb 15 22:12:16 CST 2020, time=2020-02-15, status=1, ipAttribution=)]
    2020-07-20 lujian

    #实验性#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1968141, encodeId=6e9e196814191, content=<a href='/topic/show?id=f233831582' target=_blank style='color:#2F92EE;'>#GTX-102#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8315, encryptionId=f233831582, topicName=GTX-102)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Sun Aug 30 04:45:00 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945646, encodeId=b185194564602, content=<a href='/topic/show?id=a9fa62150e8' target=_blank style='color:#2F92EE;'>#核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62150, encryptionId=a9fa62150e8, topicName=核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49cf452, createdName=xsm918, createdTime=Fri May 01 06:45:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989500, encodeId=5cef198950068, content=<a href='/topic/show?id=941d251492' target=_blank style='color:#2F92EE;'>#Angelman综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2514, encryptionId=941d251492, topicName=Angelman综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Nov 02 04:45:00 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040761, encodeId=f2f22040e61ab, content=<a href='/topic/show?id=5887461103d' target=_blank style='color:#2F92EE;'>#实验性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46110, encryptionId=5887461103d, topicName=实验性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Jul 20 13:45:00 CST 2020, time=2020-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700420, encodeId=f6361e0042040, content=<a href='/topic/show?id=2f93465966d' target=_blank style='color:#2F92EE;'>#寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46596, encryptionId=2f93465966d, topicName=寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=491a30091205, createdName=DEXTER3149, createdTime=Sat Jan 09 23:45:00 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431757, encodeId=4e6d1431e5790, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575373, encodeId=9a0f15e537311, content=<a href='/topic/show?id=03753e66414' target=_blank style='color:#2F92EE;'>#反义寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37664, encryptionId=03753e66414, topicName=反义寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfc816121587, createdName=fyxzlh, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=379288, encodeId=2bcb3e928847, content=学习中学习中谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJm4xPKAf4u6XWj35VVrjsS7zV0iceXLnUFyPcpCEs1Zws5knTcAxG7qOtflUuDHnbmVwUSbawnTUw/132, createdBy=4bea5277230, createdName=lian6388, createdTime=Sat Feb 15 22:12:16 CST 2020, time=2020-02-15, status=1, ipAttribution=)]
    2021-01-09 DEXTER3149

    #寡核苷酸#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1968141, encodeId=6e9e196814191, content=<a href='/topic/show?id=f233831582' target=_blank style='color:#2F92EE;'>#GTX-102#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8315, encryptionId=f233831582, topicName=GTX-102)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Sun Aug 30 04:45:00 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945646, encodeId=b185194564602, content=<a href='/topic/show?id=a9fa62150e8' target=_blank style='color:#2F92EE;'>#核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62150, encryptionId=a9fa62150e8, topicName=核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49cf452, createdName=xsm918, createdTime=Fri May 01 06:45:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989500, encodeId=5cef198950068, content=<a href='/topic/show?id=941d251492' target=_blank style='color:#2F92EE;'>#Angelman综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2514, encryptionId=941d251492, topicName=Angelman综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Nov 02 04:45:00 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040761, encodeId=f2f22040e61ab, content=<a href='/topic/show?id=5887461103d' target=_blank style='color:#2F92EE;'>#实验性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46110, encryptionId=5887461103d, topicName=实验性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Jul 20 13:45:00 CST 2020, time=2020-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700420, encodeId=f6361e0042040, content=<a href='/topic/show?id=2f93465966d' target=_blank style='color:#2F92EE;'>#寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46596, encryptionId=2f93465966d, topicName=寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=491a30091205, createdName=DEXTER3149, createdTime=Sat Jan 09 23:45:00 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431757, encodeId=4e6d1431e5790, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575373, encodeId=9a0f15e537311, content=<a href='/topic/show?id=03753e66414' target=_blank style='color:#2F92EE;'>#反义寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37664, encryptionId=03753e66414, topicName=反义寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfc816121587, createdName=fyxzlh, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=379288, encodeId=2bcb3e928847, content=学习中学习中谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJm4xPKAf4u6XWj35VVrjsS7zV0iceXLnUFyPcpCEs1Zws5knTcAxG7qOtflUuDHnbmVwUSbawnTUw/132, createdBy=4bea5277230, createdName=lian6388, createdTime=Sat Feb 15 22:12:16 CST 2020, time=2020-02-15, status=1, ipAttribution=)]
    2020-02-17 zhouqu_8

    #综合征#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1968141, encodeId=6e9e196814191, content=<a href='/topic/show?id=f233831582' target=_blank style='color:#2F92EE;'>#GTX-102#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8315, encryptionId=f233831582, topicName=GTX-102)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Sun Aug 30 04:45:00 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945646, encodeId=b185194564602, content=<a href='/topic/show?id=a9fa62150e8' target=_blank style='color:#2F92EE;'>#核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62150, encryptionId=a9fa62150e8, topicName=核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49cf452, createdName=xsm918, createdTime=Fri May 01 06:45:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989500, encodeId=5cef198950068, content=<a href='/topic/show?id=941d251492' target=_blank style='color:#2F92EE;'>#Angelman综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2514, encryptionId=941d251492, topicName=Angelman综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Nov 02 04:45:00 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040761, encodeId=f2f22040e61ab, content=<a href='/topic/show?id=5887461103d' target=_blank style='color:#2F92EE;'>#实验性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46110, encryptionId=5887461103d, topicName=实验性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Jul 20 13:45:00 CST 2020, time=2020-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700420, encodeId=f6361e0042040, content=<a href='/topic/show?id=2f93465966d' target=_blank style='color:#2F92EE;'>#寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46596, encryptionId=2f93465966d, topicName=寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=491a30091205, createdName=DEXTER3149, createdTime=Sat Jan 09 23:45:00 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431757, encodeId=4e6d1431e5790, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575373, encodeId=9a0f15e537311, content=<a href='/topic/show?id=03753e66414' target=_blank style='color:#2F92EE;'>#反义寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37664, encryptionId=03753e66414, topicName=反义寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfc816121587, createdName=fyxzlh, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=379288, encodeId=2bcb3e928847, content=学习中学习中谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJm4xPKAf4u6XWj35VVrjsS7zV0iceXLnUFyPcpCEs1Zws5knTcAxG7qOtflUuDHnbmVwUSbawnTUw/132, createdBy=4bea5277230, createdName=lian6388, createdTime=Sat Feb 15 22:12:16 CST 2020, time=2020-02-15, status=1, ipAttribution=)]
    2020-02-17 fyxzlh

    #反义寡核苷酸#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1968141, encodeId=6e9e196814191, content=<a href='/topic/show?id=f233831582' target=_blank style='color:#2F92EE;'>#GTX-102#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8315, encryptionId=f233831582, topicName=GTX-102)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Sun Aug 30 04:45:00 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945646, encodeId=b185194564602, content=<a href='/topic/show?id=a9fa62150e8' target=_blank style='color:#2F92EE;'>#核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62150, encryptionId=a9fa62150e8, topicName=核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49cf452, createdName=xsm918, createdTime=Fri May 01 06:45:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989500, encodeId=5cef198950068, content=<a href='/topic/show?id=941d251492' target=_blank style='color:#2F92EE;'>#Angelman综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2514, encryptionId=941d251492, topicName=Angelman综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Nov 02 04:45:00 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040761, encodeId=f2f22040e61ab, content=<a href='/topic/show?id=5887461103d' target=_blank style='color:#2F92EE;'>#实验性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46110, encryptionId=5887461103d, topicName=实验性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Jul 20 13:45:00 CST 2020, time=2020-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700420, encodeId=f6361e0042040, content=<a href='/topic/show?id=2f93465966d' target=_blank style='color:#2F92EE;'>#寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46596, encryptionId=2f93465966d, topicName=寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=491a30091205, createdName=DEXTER3149, createdTime=Sat Jan 09 23:45:00 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431757, encodeId=4e6d1431e5790, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575373, encodeId=9a0f15e537311, content=<a href='/topic/show?id=03753e66414' target=_blank style='color:#2F92EE;'>#反义寡核苷酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37664, encryptionId=03753e66414, topicName=反义寡核苷酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfc816121587, createdName=fyxzlh, createdTime=Mon Feb 17 08:45:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=379288, encodeId=2bcb3e928847, content=学习中学习中谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJm4xPKAf4u6XWj35VVrjsS7zV0iceXLnUFyPcpCEs1Zws5knTcAxG7qOtflUuDHnbmVwUSbawnTUw/132, createdBy=4bea5277230, createdName=lian6388, createdTime=Sat Feb 15 22:12:16 CST 2020, time=2020-02-15, status=1, ipAttribution=)]
    2020-02-15 lian6388

    学习中学习中谢谢分享

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