NEJM:II型糖尿病人群通过正规治疗可有效降低其死亡及心血管事件风险

2018-08-16 zhangfan MedSci原创

研究认为,各项指标均得到有效控制的II型糖尿病患者其全因死亡、心肌梗死以及中风风险与一般人群相当,这一研究结果再次强调了糖尿病人群接受正规治疗的重要性

糖尿病人群的死亡及血管事件风险较高,近日研究人员开展真实世界研究对II型糖尿病患者的死亡及血管事件风险进行了考察。

研究在瑞典开展,271174名II型糖尿病患者以及1355870名对照志愿者参与,依据年龄以及5个糖尿病风险因素(糖化血红蛋白水平、低密度脂蛋白胆固醇水平、蛋白尿、吸烟和高血压)对患者分层,采用COX回归模型考察糖尿病患者死亡、急性心肌梗塞、中风以及心衰住院风险以及上述风险与糖尿病风险因素之间的关系。

研究随访5.7年,总计175345人死亡。II型糖尿病人群中,有效控制糖尿病风险因素可降低患者死亡风险,将5种风险因素均控制在目标范围内的人群,相对于对照组其全因死亡(HR=1.06)、心肌梗死(HR=0.84)以及中风(HR=0.95)风险相当,但心衰风险始终较高(HR=1.45)。对于II型糖尿病人群,糖化血红蛋白水平是中风以及急性心肌梗死最重要的风险因素,吸烟是最重要的死亡风险因素。

研究认为,各项指标均得到有效控制的II型糖尿病患者其全因死亡、心肌梗死以及中风风险与一般人群相当,这一研究结果再次强调了糖尿病人群接受正规治疗的重要性。

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    2018-08-17 flysky120

    控制好血糖戒烟每个患者都应该做到。

    0

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    2018-08-16 misszhang

    谢谢MedSci提供最新的资讯

    0

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