Gastrointest Endosc:Barrett食管发展成食管肿瘤的风险!

2021-02-07 Nebula MedSci原创

Barrett食管是食管癌的唯一明确的癌前病变。

Barrett食管(BE),即食管远端的鳞状上皮化生成了带有杯状细胞的柱状上皮,多见于慢性胃食管反流病患者。Barrett食管是食管癌的唯一明确的癌前病变。目前对携带不确定异型增生(IND)的Barrett食管(BE-IND)患者肿瘤进展风险的认识还是来源于小型回顾性和病理学登记研究。 本研究是一项多中心队列研究,旨在确定BE-IND患者的肿瘤发病率。 研究流程 纳入了来自2个学术中心的确诊为BE-IND的患者,如果受试患者既往无异型增生的证据,则接受长达1年及以上的内镜随访(FU)。 无肿瘤存活率 1997年-2017年期间,共筛查了465例BE-IND患者,排除了223例(48.0%)。在纳入分析的242例患者中,184例(76.0%)在随访期间未发现异型增生。23例(9.5%)患者存在肿瘤(低度异型增生[LGD]20例、高度异型增生[HGD]2例、粘膜内癌[IMC]1例);中位随访了1.5年(IQR 0.6-3.2年)后,35例(14.5%)新发肿瘤(LGD 27例,HGD 5例,IMC 3例)。 BE长度与发生肿瘤的相关性 所有肿瘤和HGD/IMC的发病率分别为3.2例/100

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    2021-11-25 ms3000001096233086

    学习了

    0

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encryptionId=fa761e2916a, topicName=Test)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Wed Oct 27 17:00:30 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971785, encodeId=eca519e17854a, content=<a href='/topic/show?id=7e1010110675' target=_blank style='color:#2F92EE;'>#食管肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101106, encryptionId=7e1010110675, topicName=食管肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Thu Apr 22 22:00:30 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924929, encodeId=7d8b924929f6, content=积分怎么获得, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=21455386044, createdName=ms8000000911130373, createdTime=Tue Feb 16 18:40:27 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1393710, encodeId=ed5d1393e1088, content=<a href='/topic/show?id=50cc321084' target=_blank style='color:#2F92EE;'>#Barrett食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3210, encryptionId=50cc321084, topicName=Barrett食管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Tue Feb 09 13:00:30 CST 2021, time=2021-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437607, encodeId=b067143e607e4, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Feb 09 13:00:30 CST 2021, time=2021-02-09, status=1, ipAttribution=)]
    2021-10-04 ysjykql
  5. 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encryptionId=fa761e2916a, topicName=Test)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Wed Oct 27 17:00:30 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971785, encodeId=eca519e17854a, content=<a href='/topic/show?id=7e1010110675' target=_blank style='color:#2F92EE;'>#食管肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101106, encryptionId=7e1010110675, topicName=食管肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Thu Apr 22 22:00:30 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924929, encodeId=7d8b924929f6, content=积分怎么获得, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, 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objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Feb 09 13:00:30 CST 2021, time=2021-02-09, status=1, ipAttribution=)]
    2021-07-11 许安
  6. 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objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Feb 09 13:00:30 CST 2021, time=2021-02-09, status=1, ipAttribution=)]
    2021-10-27 lqvr
  7. 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encryptionId=fa761e2916a, topicName=Test)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Wed Oct 27 17:00:30 CST 2021, time=2021-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971785, encodeId=eca519e17854a, content=<a href='/topic/show?id=7e1010110675' target=_blank style='color:#2F92EE;'>#食管肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101106, encryptionId=7e1010110675, topicName=食管肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Thu Apr 22 22:00:30 CST 2021, time=2021-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924929, encodeId=7d8b924929f6, content=积分怎么获得, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, 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objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Feb 09 13:00:30 CST 2021, time=2021-02-09, status=1, ipAttribution=)]
  8. 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    2021-02-16 ms8000000911130373

    积分怎么获得

    0

  9. 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    2021-02-09 zhouqu_8

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