Circ-Cardiovasc Int:FFR指导的搭桥手术可大幅降低死亡风险

2018-06-07 xujing 中国循环杂志

根据《循环·心血管介入》杂志发表的研究结果,与传统冠脉造影指导的冠状动脉旁路移植术相比,血流储备分数(FFR)指导的冠状动脉旁路移植术能显著降低总死亡率或心肌梗死发生率。

根据《循环·心血管介入》杂志发表的研究结果,与传统冠脉造影指导的冠状动脉旁路移植术相比,血流储备分数(FFR)指导的冠状动脉旁路移植术能显著降低总死亡率或心肌梗死发生率。
 
研究者回顾性分析了2006~2010年间接受CABG治疗的627例患者,其中,198例患者根据FFR至少1处狭窄进行搭桥,而429例患者根据冠脉造影对所有狭窄进行了搭桥。

FFR指导组患者较年轻(66岁vs 70岁),男性更常见(82% vs 72%),较糖尿病患者少(21% vs 30%)。
 
396例患者按1:1倾向评分匹配的年龄,性别和糖尿病状态的临床随访分析。
 
随访6年,与冠脉造影引导组相比,FFR指导组患者的全因死亡率/心肌梗死发生率较低(16% vs 25%;HR=0.59;95% CI,0.33-0.93%),而FFR指导组的MACE发生率较低(21% vs 26%;HR=0.77;95% CI,0.1-1.16)。

原始出处:Stephane Fournier, Gabor G. Toth, Bernard De Bruyne, et al. Six-Year Follow-Up of Fractional Flow Reserve-Guided Versus Angiography-Guided Coronary Artery Bypass Graft Surgery. Circulation: Cardiovascular Interventions. 2018;11:e006368

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    2018-12-19 quxin068
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    2018-06-16 飘飘爱

    很好

    0

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    2018-06-10 三生有幸9135

    学习一下谢谢

    0

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    2018-06-08 虈亣靌

    了解一下.谢谢分享!

    0

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