Stroke:急性脑干梗死早期神经功能恶化的预测因素

2019-12-04 xing.T MedSci原创

由此可见,这些结果表明梗死部位最大长度乘以厚度可能是评估孤立性急性桥脑梗死进展的指标。沿传导束的脑桥梗死程度可能导致神经功能恶化。

急性桥脑梗死患者梗死面积与神经功能进展之间的关系尚不清楚。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,这项研究旨在探讨磁共振成像对急性桥脑梗死早期神经功能恶化(END)的形态学预测价值。

研究人员将所有急性缺血性脑卒中入院患者纳入研究。研究人员测量了梗死部位腹背侧长度乘以厚度作为梗死面积的参数。END定义为美国国立卫生研究院卒中量表评分在入院后第一周内运动能力增加≥1分或总得分增加≥2分。

研究人员共登记了407例患者,其中114例(28.0) %)患者被诊断为END。调整后的Logistic回归分析显示最大长度乘以厚度与END独立相关(比值比为4.580[95%CI为2.909-7.210])。在受试者工作特性曲线分析中,梗死部位最大长度乘以厚度来预测END时,灵敏度、特异性和曲线下面积分别为77.2%、79.2%和0.843。

由此可见,这些结果表明梗死部位最大长度乘以厚度可能是评估孤立性急性桥脑梗死进展的指标。沿传导束的脑桥梗死程度可能导致神经功能恶化。 

原始出处:

Haiyan Li.et al.Predictors of Early Neurologic Deterioration in Acute Pontine Infarction.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027239

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    2019-12-06 qingfengqishi5

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