BMC Res Notes:较高的VB6,叶酸和VB12的摄入量与较低冠心病的发病风险相关

2019-09-16 不详 网络

本研究旨在量化B族维生素摄入量与未来冠心病(CHD)风险之间的关系。PubMed和Scopus进行了系统检索,纳入2018年4月30日之前评估叶酸,维生素B6和维生素B12的摄入量与普通人群中CHD风险关系的前瞻性队列研究。进行了随机效应荟萃分析。 共有11项前瞻性队列研究(总人数n = 369,746),包括5133例冠心病患者被纳入分析。结果显示,叶酸摄入量增加250μg/d时,相对风险为0.

本研究旨在量化B族维生素摄入量与未来冠心病(CHD)风险之间的关系。

PubMed和Scopus进行了系统检索,纳入2018年4月30日之前评估叶酸,维生素B6和维生素B12的摄入量与普通人群中CHD风险关系的前瞻性队列研究。进行了随机效应荟萃分析。

共有11项前瞻性队列研究(总人数n = 369,746),包括5133例冠心病患者被纳入分析。结果显示,叶酸摄入量增加250μg/d时,相对风险为0.79(95%CI:0.69,0.89; I2 = 67%); 维生素B6摄入量增加0.5 mg/d时,相对风险为0.87(95%CI:0.78,0.96; I2 = 80%);维生素B12摄入量增加3μg/d时,相对风险为0.97(95%CI:0.80,1.14:I2 = 67%)。当分析仅限于膳食维生素摄入时,结果没有实质性改变。非线性剂量反应荟萃分析显示,叶酸和维生素B6摄入量与冠心病风险之间呈线性负相关关系。

总之,该研究结果显示,较高的叶酸和维生素B6摄入量与普通人群较低的冠心病的风险相关。

原始出处:

Becerra SC, Roy DC, et al., An optimized staining technique for the detection of Gram positive and Gram negative bacteria within tissue. BMC Res Notes. 2016 Apr 12;9:216. doi: 10.1186/s13104-016-1902-0.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1013152, encodeId=6969101315257, content=是不是与VB6,叶酸和VB12有参与同型半胱氨酸的代谢有关呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210906/83f713f2b62c4aee8b44c4aef98da86a/6bf2c9934b67479882ef7b281510b82c.jpg, createdBy=69654767868, createdName=wangxccool, createdTime=Tue Aug 31 11:20:33 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860652, encodeId=c29a18606526e, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Wed Dec 11 03:26:00 CST 2019, time=2019-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974954, encodeId=637a19e495463, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Thu Jun 11 07:26:00 CST 2020, time=2020-06-11, status=1, ipAttribution=)]
    2021-08-31 wangxccool

    是不是与VB6,叶酸和VB12有参与同型半胱氨酸的代谢有关呢?

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1013152, encodeId=6969101315257, content=是不是与VB6,叶酸和VB12有参与同型半胱氨酸的代谢有关呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210906/83f713f2b62c4aee8b44c4aef98da86a/6bf2c9934b67479882ef7b281510b82c.jpg, createdBy=69654767868, createdName=wangxccool, createdTime=Tue Aug 31 11:20:33 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860652, encodeId=c29a18606526e, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Wed Dec 11 03:26:00 CST 2019, time=2019-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974954, encodeId=637a19e495463, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Thu Jun 11 07:26:00 CST 2020, time=2020-06-11, status=1, ipAttribution=)]
    2019-12-11 lmm397
  3. [GetPortalCommentsPageByObjectIdResponse(id=1013152, encodeId=6969101315257, content=是不是与VB6,叶酸和VB12有参与同型半胱氨酸的代谢有关呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210906/83f713f2b62c4aee8b44c4aef98da86a/6bf2c9934b67479882ef7b281510b82c.jpg, createdBy=69654767868, createdName=wangxccool, createdTime=Tue Aug 31 11:20:33 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860652, encodeId=c29a18606526e, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Wed Dec 11 03:26:00 CST 2019, time=2019-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974954, encodeId=637a19e495463, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Thu Jun 11 07:26:00 CST 2020, time=2020-06-11, status=1, ipAttribution=)]
    2020-06-11 仁医06