Hypertension.:成人高血压诊断 动态血压监测更划算?

2019-01-10 吴星 环球医学

既往成本效果模型发现,动态血压监测(ABPM)是诊断高血压的一个有利策略,但是这种策略大都聚焦于临床血压(BP)筛查阳性的老年人群。2019年1月,发表在《Hypertension》的一项研究调查了,在美国成人高血压诊断中,临床血压测量、家庭血压监测和2种情况下的动态血压监测测量的成本效果。

既往成本效果模型发现,动态血压监测(ABPM)是诊断高血压的一个有利策略,但是这种策略大都聚焦于临床血压(BP)筛查阳性的老年人群。2019年1月,发表在《Hypertension》的一项研究调查了,在美国成人高血压诊断中,临床血压测量、家庭血压监测和2种情况下的动态血压监测测量的成本效果。

研究者评价了初级医疗机构中14个年龄和性别进行分层的假设队列(年龄≥21岁的成人)的3种血压测量方法的成本效果,解释测量中假阳性(白大衣高血压)和假阴性(隐匿性高血压)的可能性。

研究者比较了质量调整生命年和生命周期成本(基于美国卫生保健的视角,2017年,美元)相关临床血压测量、家庭血压监测和2种情况下的动态血压监测:初始测量为阳性或阴性。

从已发表文献、可公开获得的数据资源以及专家输入,获得模型参数。在筛查阳性的情况中,动态血压监测是所有年龄和性别组中的优势策略。与临床血压测量相比,动态血压监测与成本节约$77(80岁女性)至$5013(21岁女性)相关。在筛查阴性的情况中,动态血压监测是所有男性和年龄<80岁女性的主要策略,节约成本$128(70岁女性)至$2794(21岁女性)。

敏感性分析显示,结果对测量特异性和降压药成本敏感。无论初始筛查结果如何,动态血压监测均被推荐作为初级医疗中大部分成人的诊断策略。

原始出处:

Beyhaghi H, Viera AJ. et.al. Comparative Cost-Effectiveness of Clinic, Home, or Ambulatory Blood Pressure Measurement for Hypertension Diagnosis in US Adults. Hypertension. 2019 Jan;73(1):121-131. doi: 10.1161/HYPERTENSIONAHA.118.11715.

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北京儿童医院血液肿瘤中心、北京博仁医院血液三科主任医师张永红教授告诉搜狐健康,淋巴瘤虽然是危险的恶性肿瘤,但也是治愈性极高的一种肿瘤,特别是对儿童来说。近年来,随着采用国际规范的治疗方案,大多数儿童淋巴瘤治愈率在80%以上,其中霍奇金淋巴瘤的5年无病生存率更是高达90%以上。