Nature:人类胚胎研究突破性进展:宫外存活13天

2016-05-07 MedSci MedSci原创

在人类胚胎发育的研究领域有着14天的时间限制。 腾讯科学讯 据英国《独立报》报道,科学家们在实验室中培育的一个人类胚胎成功存活了13天时间,这已经打破了之前的记录,但是这项研究同时也带来了关于生命起源时间的新理论争论。 自从1969年科学家们首次在试管中进行胚胎受精实验以来,他们从未成功让胚胎在体外存活超过7天时间。然而剑桥大学的科学家们现在已经成功让胚胎在子宫外存活了13


人类胚胎研究突破性进展:宫外存活13天

在人类胚胎发育的研究领域有着14天的时间限制。

腾讯科学讯 据英国《独立报》报道,科学家们在实验室中培育的一个人类胚胎成功存活了13天时间,这已经打破了之前的记录,但是这项研究同时也带来了关于生命起源时间的新理论争论。

自从1969年科学家们首次在试管中进行胚胎受精实验以来,他们从未成功让胚胎在体外存活超过7天时间。然而剑桥大学的科学家们现在已经成功让胚胎在子宫外存活了13天,但是他们不得不避开目前关于14天的伦理道德限制。

在实验室中观察生命这一最神秘的发展过程,能够让研究人员们更多的了解遗传疾病和残疾。研究人员称,这项研究能够帮助他们改善试管受精的失败率(目前的失败率高达70%),而且能够让他们更好的了解流产这一过程。

更多的了解人类早期胚胎的发育或许也能够让医学领域最大的希望早日实现,也就是我们所说的干细胞再生医学。干细胞能够转变成为任何不同的细胞,而且医生们认为干细胞未来有一天能够用于治疗老年痴呆、心脏病和许多其它疾病。

这项突破性研究能够引发人们呼吁政府考虑放松法律方面的限制,但是这样的做法也会带来巨大的争议。14天这一限制与人类的生物学变化有关,这一限制是在20世纪80年代制定的,因为科学家们认为这一时间点是人与胚胎界定的一个转折点。

这项研究的负责人之一Magdalena Zernicka-Goetz教授强调了能够观察一个生长了13天的胚胎所能带来的好处。她声称:“我们首次能够能够研究在这一关键时期的人类胚胎发育。这真的是我们人类发育最神秘的阶段。”

她声称:“试管受精在人类发展史上是一个里程碑,因为从这一阶段开始胚胎就开始真正成形,并且身体的发育方向就已经决定下来。这也是我们能够检测到许多发育缺陷的孕育阶段。但是在此之前,我们无法深入研究人类胚胎的这一阶段。”


原始出处:

Shahbazi MN, Jedrusik A, Vuoristo S, Recher G, Hupalowska A, Bolton V, Fogarty NM, Campbell A, Devito LG, Ilic D, Khalaf Y, Niakan KK, Fishel S, Zernicka-Goetz M. Self-organization of the human embryo in the absence of maternal tissues. Nat Cell Biol. 2016 May 4. doi: 10.1038/ncb3347.


Deglincerti A, Croft GF, Pietila LN, Zernicka-Goetz M, Siggia ED, Brivanlou AH. Self-organization of the in vitro attached human embryo. Nature. 2016 May 4. doi: 10.1038/nature17948

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    2016-07-06 liye789132251
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    2016-05-09 jaysppr

    太违背伦理了这样

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2083793, encodeId=df4e2083e93c2, content=<a href='/topic/show?id=285be342772' target=_blank style='color:#2F92EE;'>#研究突破#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73427, encryptionId=285be342772, topicName=研究突破)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbf451, createdName=陈吴1234, createdTime=Fri Jun 24 03:51:00 CST 2016, time=2016-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1881024, encodeId=13fe1881024b2, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Jul 06 03:51:00 CST 2016, time=2016-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84949, encodeId=ebcf849495d, content=太违背伦理了这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEIsrUxHnicsiaqwzJibCks60HOicbEAgbNzUiciboMJDzsWg16OHTeNHhyYvTg6TDXTlOx7icnhttCYYe2ujYt0yND7dYusOsibl9XnQCE/0, createdBy=7ad21722200, createdName=jaysppr, createdTime=Mon May 09 10:44:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1315284, encodeId=c10c13152846c, content=<a href='/topic/show?id=6fcc83e0554' target=_blank style='color:#2F92EE;'>#胚胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83705, encryptionId=6fcc83e0554, topicName=胚胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6393434, createdName=ailian1202, createdTime=Mon May 09 09:51:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84798, encodeId=85c084e9821, content=不一样啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 20:59:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84691, encodeId=aaed84691e7, content=去学习吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 12:55:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84682, encodeId=ecf38468204, content=为科学呐喊, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Sun May 08 11:05:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84617, encodeId=66a18461eb3, content=nature做的东西就是不一样,真的是创造性的东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 01:38:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84558, encodeId=2c598455899, content=重大突破, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat May 07 21:11:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84559, encodeId=edc2845592e, content=高大上啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat May 07 21:11:00 CST 2016, time=2016-05-07, status=1, ipAttribution=)]
    2016-05-09 ailian1202
  5. [GetPortalCommentsPageByObjectIdResponse(id=2083793, encodeId=df4e2083e93c2, content=<a href='/topic/show?id=285be342772' target=_blank style='color:#2F92EE;'>#研究突破#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73427, encryptionId=285be342772, topicName=研究突破)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbf451, createdName=陈吴1234, createdTime=Fri Jun 24 03:51:00 CST 2016, time=2016-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1881024, encodeId=13fe1881024b2, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Jul 06 03:51:00 CST 2016, time=2016-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84949, encodeId=ebcf849495d, content=太违背伦理了这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEIsrUxHnicsiaqwzJibCks60HOicbEAgbNzUiciboMJDzsWg16OHTeNHhyYvTg6TDXTlOx7icnhttCYYe2ujYt0yND7dYusOsibl9XnQCE/0, createdBy=7ad21722200, createdName=jaysppr, createdTime=Mon May 09 10:44:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1315284, encodeId=c10c13152846c, content=<a href='/topic/show?id=6fcc83e0554' target=_blank style='color:#2F92EE;'>#胚胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83705, encryptionId=6fcc83e0554, topicName=胚胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6393434, createdName=ailian1202, createdTime=Mon May 09 09:51:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84798, encodeId=85c084e9821, content=不一样啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 20:59:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84691, encodeId=aaed84691e7, content=去学习吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 12:55:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84682, encodeId=ecf38468204, content=为科学呐喊, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Sun May 08 11:05:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84617, encodeId=66a18461eb3, content=nature做的东西就是不一样,真的是创造性的东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 01:38:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84558, encodeId=2c598455899, content=重大突破, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat May 07 21:11:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84559, encodeId=edc2845592e, content=高大上啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat May 07 21:11:00 CST 2016, time=2016-05-07, status=1, ipAttribution=)]
    2016-05-08 stead

    不一样啊

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2083793, encodeId=df4e2083e93c2, content=<a href='/topic/show?id=285be342772' target=_blank style='color:#2F92EE;'>#研究突破#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73427, encryptionId=285be342772, topicName=研究突破)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbf451, createdName=陈吴1234, createdTime=Fri Jun 24 03:51:00 CST 2016, time=2016-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1881024, encodeId=13fe1881024b2, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Jul 06 03:51:00 CST 2016, time=2016-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84949, encodeId=ebcf849495d, content=太违背伦理了这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEIsrUxHnicsiaqwzJibCks60HOicbEAgbNzUiciboMJDzsWg16OHTeNHhyYvTg6TDXTlOx7icnhttCYYe2ujYt0yND7dYusOsibl9XnQCE/0, createdBy=7ad21722200, createdName=jaysppr, createdTime=Mon May 09 10:44:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1315284, encodeId=c10c13152846c, content=<a href='/topic/show?id=6fcc83e0554' target=_blank style='color:#2F92EE;'>#胚胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83705, encryptionId=6fcc83e0554, topicName=胚胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6393434, createdName=ailian1202, createdTime=Mon May 09 09:51:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84798, encodeId=85c084e9821, content=不一样啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 20:59:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84691, encodeId=aaed84691e7, content=去学习吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 12:55:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84682, encodeId=ecf38468204, content=为科学呐喊, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Sun May 08 11:05:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84617, encodeId=66a18461eb3, content=nature做的东西就是不一样,真的是创造性的东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sun May 08 01:38:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84558, encodeId=2c598455899, content=重大突破, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat May 07 21:11:00 CST 2016, time=2016-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=84559, encodeId=edc2845592e, content=高大上啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat May 07 21:11:00 CST 2016, time=2016-05-07, status=1, ipAttribution=)]
    2016-05-08 stead

    去学习吧

    0

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    2016-05-08 老段

    为科学呐喊

    0

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    2016-05-08 stead

    nature做的东西就是不一样,真的是创造性的东西

    0

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    2016-05-07 李继凯

    重大突破

    0

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    2016-05-07 李继凯

    高大上啊

    0

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