JNCI:祸不单行,结直肠癌患者糖尿病风险更高!

2016-03-05 Mechront 译 MedSci原创

糖尿病患者结直肠癌(CRC)风险会增加,那么CRC幸存者的糖尿病风险呢?研究者进行了一项研究,探究CRC患者的糖尿病发生率是否高于对照组。

背景:糖尿病患者结直肠癌(CRC)风险会增加,那么CRC幸存者的糖尿病风险呢?研究者进行了一项研究,探究CRC患者的糖尿病发生率是否高于对照组。

方法:使用加拿大安大略省基于人群的数据,纳入了39 707名CRC患者,按年龄、性别以1:5匹配198 535名对照组。通过病因特异性风险模型估计总的和不同亚组的糖尿病风险。

结果:平均随访4.81年,CRC和糖尿病间的联系如下:诊断CRC后第一年,CRC组与对照组相比,糖尿病风险高53%(HR = 1.53, 95% CI= 1.42 to 1.64);到第五年,糖尿病风险仍高19%(HR =
1.19, 95% CI = 1.05 to 1.35)。结肠癌、接受系统性化疗或非转移患者亚组间的CRC和糖尿病风险相似。

结论:CRC患者有更高的糖尿病风险,就算到诊断CRC的第五年,风险仍高。研究者建议对这类糖尿病高危人群进行积极的糖尿病筛查,及时纠正糖尿病危险因素。

原始出处:


Singh
S, Earle CC,et al.Incidence of Diabetes in Colorectal Cancer Survivors.J Natl
Cancer Inst. 2016 Feb 2;108(6). pii: djv402. doi: 10.1093/jnci/djv402. Print
2016 Jun

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    2016-03-26 白兔糖

    标题党

    0

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    2016-03-07 jetleo

    不能说明是高危人群吧,可能都是饮食习惯造成的

    0

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    2016-03-07 jetleo

    CRC患者有更高的糖尿病风险

    0

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