Gastroenterology:结肠息肉大小,切除方式与不完全切除风险

2020-10-19 MedSci原创 MedSci原创

1-20mm的结肠息肉经常通常不彻底,10mm或更大息肉的不彻底切除风险更大。对于1-10mm息肉,冷热勒除器的切除效果相当,而对于1-5mm息肉,勒除器的切除效果优于手术钳

肿瘤性结直肠息肉的不完全切除可导致结肠镜检查后结直肠癌风险增加。近日研究人员进行了系统综述及荟萃分析,以确定结直肠息肉的不完全切除率(IRR) 及其相关影响因素。
 
研究人员搜索了MEDLINE、EMBASE、EBM评论和CINAHL相关数据,涉及1至20毫米息肉IRRs的全文,截至2019年3月。排除标准为炎症性肠病队列研究、难治性息肉切除术的转诊、息肉大小大于20 mm,内镜下黏膜下切除和/或多切除入路。IRR的计算依据的是在息肉切除术部位取得的活检结果或切除息肉边缘的评估。主要结果是1-20mm息肉的IRR。次要结果包括1-10 mm和10-20 mm息肉的IRR,1-10 mm和10-20 mm的热或冷息肉勒除器去除的IRR,带或不带粘膜下注射勒除的IRR,1-5 mm息肉手术钳和冷勒除器去除的IRR。
 
检索到6148项研究,其中32项研纳入荟萃分析究,总共进行了9282个息肉切除。勒除器去除1-20 mm息肉的IRR为13.8%(13项研究,5128例息肉切除术)。勒除器去除1-10mm息肉的IRR为15.9%(9项研究,2531例息肉切除术),勒除器去除10-20mm息肉的IRR为20.8%(6项研究,412例息肉切除术)。热勒除器切除1-10mm息肉的IRR为14.2%,而冷勒除器1-10mm切除的IRR为17.3%。手术钳切除1-5mm息肉的IRR为9.9%,而勒除器1-5mm息肉切除术的IRR为4.4%。
 
研究发现,1-20mm的结肠息肉经常通常不彻底,10mm或更大息肉的不彻底切除风险更大。对于1-10mm息肉,冷热勒除器的切除效果相当,而对于1-5mm息肉,勒除器的切除效果优于手术钳。
 
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    2020-11-07 许安
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  5. [GetPortalCommentsPageByObjectIdResponse(id=2073146, encodeId=645920e314689, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Nov 07 18:45:52 CST 2020, time=2020-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712587, encodeId=0dc11e12587f3, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue Apr 27 12:45:52 CST 2021, time=2021-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2065188, encodeId=703f2065188ed, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Mon Jun 21 13:45:52 CST 2021, time=2021-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1505117, encodeId=f267150511e08, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Wed Oct 21 10:45:52 CST 2020, time=2020-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893229, encodeId=04e38932295c, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=023b2280938, createdName=121c5fb7m00暂无昵称, createdTime=Tue Oct 20 08:44:34 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893223, encodeId=3d0b8932231f, content=学习了👏👏, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/4zKLZ8AJ5h2w9fmdxUB9VUaaY24rbw13rlKGKUjJ0nObhPK3dtrA3icia4uJwsa2enzTiaCRKoCtkpDQr8AwutKYw/132, createdBy=59a75268895, createdName=haoguodong, createdTime=Tue Oct 20 08:36:55 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893147, encodeId=24a889314e8c, content=真棒啊!!!!!!!!!!!!!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b675329087, createdName=522801585_47232776, createdTime=Mon Oct 19 20:44:23 CST 2020, time=2020-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893141, encodeId=1c0289314105, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201019/02cc8286326947f4b8a164390bc5251e/c9669c8b986f4e8fbecd6fdada15e97c.jpg, createdBy=846a5410281, createdName=子熙, createdTime=Mon Oct 19 20:08:21 CST 2020, time=2020-10-19, status=1, ipAttribution=)]
    2020-10-20 121c5fb7m00暂无昵称

    学习

    0

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    2020-10-20 haoguodong

    学习了👏👏

    0

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    2020-10-19 522801585_47232776

    真棒啊!!!!!!!!!!!!!!!

    0

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    2020-10-19 子熙

    学习了

    0

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