Int Arch Allergy Immunol:常年过敏原免疫疗法在过敏性鼻炎患者中疗效研究

2020-01-22 AlexYang MedSci原创

在现实生活背景下,关于比较过敏原免疫疗法(AIT)与药物治疗在常年过敏性鼻炎(AR)疗效的研究很少。最近,有研究人员在患有或者不患有哮喘的AR患者中,比较了AIT和药物治疗对症状的控制和生活质量(QOL)的效果情况。研究包括了250名患有或者不患有哮喘的AR患者,并分配到免疫治疗组(AIT加药物治疗)和对照组(只有药物治疗)。研究发现,AIT组中AR症状具有临床改善,而只进行标准的药物治疗组中对鼻

在现实生活背景下,关于比较过敏原免疫疗法(AIT)与药物治疗在常年过敏性鼻炎(AR)疗效的研究很少。最近,有研究人员在患有或者不患有哮喘的AR患者中,比较了AIT和药物治疗对症状的控制和生活质量(QOL)的效果情况。

研究包括了250名患有或者不患有哮喘的AR患者,并分配到免疫治疗组(AIT加药物治疗)和对照组(只有药物治疗)。研究发现,AIT组中AR症状具有临床改善,而只进行标准的药物治疗组中对鼻症状没有明显的影响。视觉模拟评分量表(VAS)评估的QOL和满意度评分表明,免疫治疗组的效果要比药物治疗组改善效果更好。另外,在两个AIT治疗组中,药物评分均得到了显著的改善。根据他们的结果,虽然在HDM AIT组中总的哮喘评分和哮喘控制测试评分均得到了显著的改善,而在Parietaria花粉AIT组中却没有发生变化。另外,FEV1%在AIT组中与基线值相比增加,但并不显著。另一方面,FEV1%在标准药物治疗的患者中没有任何的改善。

最后,研究人员指出,在患有或者不患有哮喘的AR患者中,常年性AIT在减少症状和改善QOL得分方面是要优于单纯的药物治疗。HDM AIT在控制哮喘症状方面要要优于Parietaria花粉AIT治疗。

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    2020-01-24 膀胱癌
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    2020-01-22 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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