J Gastroen Hepatol:亚裔人群体重指数与胃肠道肿瘤死亡风险

2018-08-09 zhangfan MedSci原创

研究发现,体重过高或过低均与胃肠道肿瘤死亡风险增加相关,其中体重指数超过25的人群肝脏及结直肠肿瘤死亡风险增加,低于25人群胃及结直肠肿瘤死亡风险较低

近日研究人员考察了亚洲人群体重指数(BMI)与胃肠道肿瘤死亡率之间的关系。

研究在韩国开展,2002-03年间510148名志愿者参与日常健康体检,随访至2013年。

10.5个随访年中,总计发生7831例胃肠道肿瘤死亡案例。BMI与总胃肠道肿瘤、结肠、肝脏以及胆囊肿瘤死亡率呈U相关,与胃癌死亡率呈L相关,与食道、肝外胆管和小肠癌呈线性相关,与胰腺癌不相关。体重指数23.5-26之间的参与者胃肠道肿瘤死亡风险最低。线性相关肿瘤中,BMI每增加5,食道癌、肝外胆管和小肠癌死亡风险分别增加0.53、1.19以及0.64。U相关以及L相关肿瘤中,BMI指数25以上人群,总体肿瘤、结肠、肝脏以及胆囊肿瘤死亡风险分别为1.19、1.30、1.28以及1.30;BMI指数25以下人群的总体胃肠道、食道、胃以及结直肠肿瘤死亡风险分别为0.81、0.43、0.70以及0.77。上述结果在调整前7年随访结果以及吸烟者后,相关性仍显著。

研究发现,体重过高或过低均与胃肠道肿瘤死亡风险增加相关,其中体重指数超过25的人群肝脏及结直肠肿瘤死亡风险增加,低于25人群胃及结直肠肿瘤死亡风险较低。

原始出处:


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    2019-03-02 xjy13
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    2019-01-27 许安
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objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfBfgWn9nXBgH1sNSiaOAKhsKpN40jDHQKqcRzovau5VibLvREN8uxnu9sKoScBicHSiaDMmbveibFdrBiaD4k4IOPwlG/0, createdBy=b5d11730951, createdName=Jackie Li, createdTime=Fri Aug 10 08:10:23 CST 2018, time=2018-08-10, status=1, ipAttribution=)]
    2018-08-12 phoebeyan520

    学习了,谢谢分享

    0

  6. 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  9. 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    2018-08-10 gwc384
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    2018-08-10 Jackie Li

    学习

    0

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