Cancer Med:猪幽门螺杆菌感染与胃黏膜相关淋巴样组织淋巴瘤结节性胃炎样外观有关

2020-03-04 不详 网络

多数患有胃黏膜相关淋巴样组织(MALT)淋巴瘤的患者感染了幽门螺杆菌,根除疗法是针对局部感染幽门螺杆菌的一线治疗方法。但是,有几份报告显示甚至在幽门螺杆菌阴性病例中根除治疗的有效性。胃内MALT淋巴瘤在内窥镜下可分为三种常见类型:浅表性,溃疡性和升高型。在过去的20年中,我们遇到了200例局部胃MALT淋巴瘤。其中只有4例(2%)表现出与结节性胃炎(胃MALT淋巴瘤样结节性胃炎样外观;M-NGA)

多数患有黏膜相关淋巴样组织(MALT)淋巴瘤的患者感染了幽门螺杆菌,根除疗法是针对局部感染幽门螺杆菌的一线治疗方法。但是,有几份报告显示甚至在幽门螺杆菌阴性病例中根除治疗的有效性。内MALT淋巴瘤在内窥镜下可分为三种常见类型:浅表性,溃疡性和升高型。在过去的20年中,我们遇到了200例局部胃MALT淋巴瘤。其中只有4例(2%)表现出与结节性胃炎(胃MALT淋巴瘤样结节性胃炎样外观;M-NGA)相似的宏观表现。

在这里,我们比较了M-NGA和其他常见类型的胃MALT淋巴瘤之间的临床病理特征和非H幽门螺杆菌(NHPH)感染率。为了检查NHPH的患病率,从4例M-NGA,20例常见内镜类型的胃MALT淋巴瘤和10例结节性胃炎的福尔马林固定石蜡包埋的活检组织中提取了DNA。使用了高度敏感的聚合酶链反应测定法来检测5种NHPH的存在(猪幽门螺杆菌,H felis,H bizzozeronii,H salomonis和H heilmannii)。

结果显示,在4例M-NGA,20例其他类型的胃MALT淋巴瘤和10例结节性胃炎患者中分别检测到4、2和0例H猪感染。在任何情况下都未检测到其他NHPH物种。在M-NGA病例中,根除疗法的完全缓解率为4/4。

因此,表型非常罕见的结节性胃炎样MALT淋巴瘤与NHPH感染密切相关,根除治疗可能是首选治疗方法。

原始出处:

Hidehiko Takigawa,  Satoshi Masaki, et al., Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa‐associated lymphoid tissue lymphoma. Cancer Med. 2019 Aug; 8(9): 4370–4379. doi: 10.1002/cam4.2314

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    2020-05-14 kcb069
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    2020-03-15 baoya
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1811813, encodeId=888b18118132f, content=<a href='/topic/show?id=751f8889423' target=_blank style='color:#2F92EE;'>#螺杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88894, encryptionId=751f8889423, topicName=螺杆菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87b1109, createdName=kcb069, createdTime=Thu May 14 18:47:00 CST 2020, time=2020-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693592, encodeId=da9a169359274, content=<a href='/topic/show?id=cb16e883013' target=_blank style='color:#2F92EE;'>#结节性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78830, encryptionId=cb16e883013, topicName=结节性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d8429436174, createdName=crystal0572, createdTime=Fri Nov 13 21:47:00 CST 2020, time=2020-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931848, encodeId=2686193184825, content=<a href='/topic/show?id=250183421dc' target=_blank style='color:#2F92EE;'>#胃黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83421, encryptionId=250183421dc, topicName=胃黏膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=743d308, createdName=baoya, createdTime=Sun Mar 15 06:47:00 CST 2020, time=2020-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1348740, encodeId=26281348e402a, content=<a href='/topic/show?id=cfeb49103af' target=_blank style='color:#2F92EE;'>#幽门螺杆菌感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49103, encryptionId=cfeb49103af, topicName=幽门螺杆菌感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520055, encodeId=c6591520055da, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555308, encodeId=4b4f1555308be, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610316, encodeId=c65b16103162e, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=380050, encodeId=16573800500d, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf2f2432532, createdName=123bc38bm68暂无昵称, createdTime=Wed Mar 04 06:09:05 CST 2020, time=2020-03-04, status=1, ipAttribution=)]
    2020-03-05 snowpeakxu
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    2020-03-05 muzishouyi
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  8. [GetPortalCommentsPageByObjectIdResponse(id=1811813, encodeId=888b18118132f, content=<a href='/topic/show?id=751f8889423' target=_blank style='color:#2F92EE;'>#螺杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88894, encryptionId=751f8889423, topicName=螺杆菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87b1109, createdName=kcb069, createdTime=Thu May 14 18:47:00 CST 2020, time=2020-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693592, encodeId=da9a169359274, content=<a href='/topic/show?id=cb16e883013' target=_blank style='color:#2F92EE;'>#结节性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78830, encryptionId=cb16e883013, topicName=结节性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d8429436174, createdName=crystal0572, createdTime=Fri Nov 13 21:47:00 CST 2020, time=2020-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931848, encodeId=2686193184825, content=<a href='/topic/show?id=250183421dc' target=_blank style='color:#2F92EE;'>#胃黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83421, encryptionId=250183421dc, topicName=胃黏膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=743d308, createdName=baoya, createdTime=Sun Mar 15 06:47:00 CST 2020, time=2020-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1348740, encodeId=26281348e402a, content=<a href='/topic/show?id=cfeb49103af' target=_blank style='color:#2F92EE;'>#幽门螺杆菌感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49103, encryptionId=cfeb49103af, topicName=幽门螺杆菌感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520055, encodeId=c6591520055da, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555308, encodeId=4b4f1555308be, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610316, encodeId=c65b16103162e, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Mar 05 15:47:00 CST 2020, time=2020-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=380050, encodeId=16573800500d, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf2f2432532, createdName=123bc38bm68暂无昵称, createdTime=Wed Mar 04 06:09:05 CST 2020, time=2020-03-04, status=1, ipAttribution=)]
    2020-03-04 123bc38bm68暂无昵称

    学习了

    0