DCR: 重复切除术在转移性结直肠癌患者中的作用

2019-05-22 不详 MedSci原创

重复手术切除在治疗转移性结直肠癌中的作用还没有明确的定论,本研究旨在探讨重复切除复发的转移性结直肠癌治疗效果。

背景:
重复手术切除在治疗转移性直肠癌中的作用还没有明确的定论,本研究旨在探讨重复切除复发的转移性直肠癌治疗效果。

方法:
这是一项多中心回顾性观察研究。纳入的患者为转移性结直肠癌患者,这些患者同时发生远处转移并同时切除原发性和远处疾病,主要观察指标是复发部位,治疗情况和生存质量。

结果:
本项研究共确定了1133名患者,其中1073名符合条件。总体而言,1073例患者的809名患者肿瘤复发后行根治性切除,323名患者行 重复切除术。其中,211 发生了复发 ; 其中80名患者接受了第二次重复切除术。43%复发仅在肺部,仅在腹膜种植者中占30%,在多器官受累者中占28%。在接受第二次重复切除术的患者中,5年总生存率分别为56%。

结论:
重复手术切除可以对转移性结直肠癌患者产生长期生存产生益处。

原始出处:
Matsumoto, Takuya. Et al. Role of Repeat Resection in Patients With Metastatic Colorectal Cancer. Diseases of the Colon & Rectum. 2019.

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    2019-05-22 txqjm

    谢谢了,学习

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