AP&T: 非选择性β受体阻滞剂增加肝硬化患者门静脉血栓形成的概率

2019-02-16 不详 MedSci原创

非恶性门静脉血栓形成是肝硬化过程中的严重并发症,会影响肝移植的成功率,甚至影响外科手术后的存活率。因此,本项研究的目的是为了确定肝硬化患者门静脉血栓形成的危险因素

背景
非恶性门静脉血栓形成是肝硬化过程中的严重并发症,会影响肝移植的成功率,甚至影响外科手术后的存活率。因此,本项研究的目的是为了确定肝硬化患者门静脉血栓形成的危险因素。

方法
研究人员分析在2014年1月至2017年2月期间的108名患有肝硬化且无门静脉血栓形成的门诊患者的临床数据,并且每3或6个月进行一次多普勒超声检查,中位随访时间为19个月。

结果
门静脉血栓在11例患者中发生。非选择性β-阻滞药物使用([HR] 10.56; 95%[CI]:1.35-82.73; P =0.025)以及中型或大型食管静脉曲张(HR 5.67; 95%CI:1.49-21.63; P  <  0.001)与门静脉血栓形成有关。非选择性β受体阻滞剂可显着降低心率和基线时门静脉血流速度(P=0.005)。

结论
本项研究结果证实门静脉血栓形成发展与食管静脉曲张有关系,非选择性β受体阻滞剂会增加这种危险发生的概率。

原始出处:

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    2019-07-03 zhyy88
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    2019-09-09 xue8602
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  5. [GetPortalCommentsPageByObjectIdResponse(id=2085815, encodeId=647e20858158a, content=<a href='/topic/show?id=723a9e69383' target=_blank style='color:#2F92EE;'>#阻滞剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97693, encryptionId=723a9e69383, topicName=阻滞剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=40be178, createdName=zhyy88, createdTime=Wed Jul 03 09:47:00 CST 2019, time=2019-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955421, encodeId=746d195542147, content=<a href='/topic/show?id=0aeb991e44c' target=_blank style='color:#2F92EE;'>#静脉血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99174, encryptionId=0aeb991e44c, topicName=静脉血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d139492, 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  6. [GetPortalCommentsPageByObjectIdResponse(id=2085815, encodeId=647e20858158a, content=<a href='/topic/show?id=723a9e69383' target=_blank style='color:#2F92EE;'>#阻滞剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97693, encryptionId=723a9e69383, topicName=阻滞剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=40be178, createdName=zhyy88, createdTime=Wed Jul 03 09:47:00 CST 2019, time=2019-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955421, encodeId=746d195542147, content=<a href='/topic/show?id=0aeb991e44c' target=_blank style='color:#2F92EE;'>#静脉血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99174, encryptionId=0aeb991e44c, topicName=静脉血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d139492, 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href='/topic/show?id=6d779e14916' target=_blank style='color:#2F92EE;'>#门静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97149, encryptionId=6d779e14916, topicName=门静脉)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Feb 18 12:47:00 CST 2019, time=2019-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483281, encodeId=ec4c14832817e, content=<a href='/topic/show?id=c82e991e71b' target=_blank style='color:#2F92EE;'>#静脉血栓形成#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99177, encryptionId=c82e991e71b, topicName=静脉血栓形成)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d387907505, createdName=ms5187542471278033, createdTime=Mon Feb 18 12:47:00 CST 2019, time=2019-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046375, encodeId=045e10463e5cb, content=谢谢!最新的信息读起来就是收获大, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Sun Feb 17 00:47:00 CST 2019, time=2019-02-17, status=1, ipAttribution=)]
    2019-11-05 fusion
  7. 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createdAvatar=, createdBy=1d387907505, createdName=ms5187542471278033, createdTime=Mon Feb 18 12:47:00 CST 2019, time=2019-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046375, encodeId=045e10463e5cb, content=谢谢!最新的信息读起来就是收获大, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Sun Feb 17 00:47:00 CST 2019, time=2019-02-17, status=1, ipAttribution=)]
    2019-02-17 guging

    谢谢!最新的信息读起来就是收获大

    0