Ann Thoracic Surg:哪种治疗方法可以很大提高肺癌患者的生存率,研究给出答案!

2018-01-03 佚名 everydayhealth

根据2017年《胸外科年鉴》在线发表的一项研究,早期非小细胞肺癌的侵袭性手术比中等强度的手术和日益流行的放射治疗方法的存活时间更长。早期肺癌被定义为局限于肺部的一部分,没有扩散到肺部或身体的其他部位的癌症。从历史上看,肺叶切除,切除肿瘤的整个肺叶,是早期肺癌的首选治疗方法。但在过去的十年中,立体定向放射治疗(SBRT),精度破坏肿瘤,高剂量辐射两周的治疗方法已经变得越来越流行。

根据2017年《胸外科年鉴》在线发表的一项研究,早期非小细胞肺癌的侵袭性手术比中等强度的手术和日益流行的放射治疗方法的存活时间更长。早期肺癌被定义为局限于肺部的一部分,没有扩散到肺部或身体的其他部位的癌症。从历史上看,肺叶切除,切除肿瘤的整个肺叶,是早期肺癌的首选治疗方法。但在过去的十年中,立体定向放射治疗(SBRT),精度破坏肿瘤,高剂量辐射两周的治疗方法已经变得越来越流行。

加利福尼亚大学圣地亚哥分校医学院的研究人员表示,哪种方法更能改善生存方面的优越性还不清楚。以前的研究试图比较每个过程的病人结局,但结果却不尽相同。在这项研究中,研究人员进行了一种对早期肺癌的最大和最详细的分析。在4069例患者的研究中,多数行肺叶切除,16%例亚肺叶切除,11%接受SBRT。研究人员发现,治疗之后的五年,在切除组有23%患者死亡,采用放射治疗的患者45%死亡,亚肺叶切除患者的死亡率是32%。

这些年来,肺叶切除术是一种越来越安全的常规手术,打开病人的胸腔,切除肿瘤的肺叶,一些外科医生采用微创技术切除肺叶,以减少切口。立体定向放射治疗不需要手术,可以在几天内完成。但最终,患者应该考虑哪种方法更可能治愈癌症呢?即使早期的肺癌也是一种危险的疾病,有很大的癌症复发风险。当观察病人的生存曲线时,并不是那么好。即使肺部只有一个结节,一些病人也会发展成晚期肺癌。因此,如果身体允许的话,研究人员还是建议手术治疗是生存希望最大的选择。

原始出处:

Alex K. Bryant,  Robert C. Mundt, Ajay P. Sandhu, et.al. Stereotactic Body Radiation Therapy Versus Surgery for Early Lung Cancer Among US Veterans. The Annals of Thoracic Surgery

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    2018-07-19 yyj062
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    2018-01-04 1771ae4158m

    学习一下很不错

    0

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    2018-01-04 明月清辉

    谢谢分享.学习了

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