卒中增加透析患者死亡风险

2015-01-27 kidney1234567 丁香园

卒中在普通人群中是灾难性事件,是致残的主要原因。 卒中在长期透析的人群中十分常见,但是目前,在透析患者中卒中与死亡率的相关性却没有很好的量化。 美国明尼苏达州亨内平县医疗中心的Wetmore教授等使用美国肾脏病数据登记系统(USRDS)和患者的医疗保险资料进行了一项大规模的回顾性的队列研究。相关结果于本月发表在CJASN杂志上。 该研究发现,透析患者死亡风险增加、后续寿命减少

卒中在普通人群中是灾难性事件,是致残的主要原因。

卒中在长期透析的人群中十分常见,但是目前,在透析患者中卒中与死亡率的相关性却没有很好的量化。

美国明尼苏达州亨内平县医疗中心的Wetmore教授等使用美国肾脏病数据登记系统(USRDS)和患者的医疗保险资料进行了一项大规模的回顾性的队列研究。相关结果于本月发表在CJASN杂志上。

该研究发现,透析患者死亡风险增加、后续寿命减少均与卒中发生有关。

谁被纳入研究范围?

2000年1月-2005年10月期间开始间隙性透析,且有医疗保险和医疗补助双重资格的患者。

共纳入了69371例患者,平均年龄是60.8岁。

卒中是笼统谈谈吗?

研究观察卒中后90天内患者的生存情况,通过调阅医疗保险资料确定90天的生存期内患者是缺血性卒中还是出血性卒中。

结果显示,每1000人年中,缺血性卒中占21.1%,出血性卒中占4.7%。

30天时,缺血性卒中和出血性卒中的死亡率分别是17.9%和53.4%。

出血性卒中和缺血性卒的死亡风险一样吗?

对于进入队列1年后即发生卒中的患者,出血性卒中引起死亡的校正风险比(AHR):

在1周时是25.4,在3个月时是9.9,在6个月时是5.9,在24个月时是1.8。

相应的缺血性卒中引起死亡的AHR:

在1周时是11.7,在3个月时是6.6,在6个月时是4.7,在48个月时仍显著>1.0。

不同种族会不会结果不一样?

出血性卒中和缺血性卒中导致寿命丢失的月数中位数分别是40.7和34.6。

对两种卒中类型而言,死亡率不因患者种族不同而有所不同。

能一句话概要下吗?

该研究发现,透析患者死亡风险增加、后续寿命减少均与卒中发生有关。

小编点评

对透析患者,应格外注意卒中的防治。


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    2015-07-29 sundong

    这个写的不错

    0

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    2015-04-11 x35042875

    轻度肾脏疾病对母亲和婴儿可能会增加孕期风险

    0

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    2015-01-27 223.104.5.**

    不用说也这样

    0

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