JCEM:SARS-CoV-2感染后长期血糖控制不受影响

2021-11-02 网络 网络

COVID-19相关的血糖异常不太可能成为一个持续的公共卫生问题。关于COVID-19肺炎后糖尿病风险的说法应谨慎解释。

与没有糖尿病的人相比,1型或2型糖尿病患者更容易患上严重的COVID-19,并死于SARS-CoV-2感染

近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,该研究旨在评估SARS-CoV-2肺炎期间诊断出的血糖异常是否会在SARS-CoV-2感染问题解决后成为潜在的公共卫生问题。在疑似COVID-19肺炎的成人队列中,研究人员将住院时的血糖数据与COVID-19发病前一年的空腹血糖(FBG)和出院后随访期间的血糖数据相结合。

2020年2月25日至5月15日,660名疑似COVID-19肺炎的成年人被送往圣拉斐尔医院(意大利米兰)。通过结构化访谈/病历审查,研究人员收集了入院时的人口统计学、临床特征和实验室检查结果以及住院期间或出院后和前一年的其他数据。入院时,研究人员根据ADA标准将参与者分类为:a)既往糖尿病;b)新诊断的糖尿病;c)不在糖尿病范围内的高血糖症;d)正常血糖。入院前和随访期间的FBG分为正常或受损的空腹血糖和糖尿病范围内的空腹血糖。

在确诊的COVID患者(n=589)中,既往或新诊断的糖尿病、非糖尿病范围内的高血糖和血糖正常的比例分别为19.6%、6.7%、43.7%和30.0%。与血糖正常的患者相比,与COVID-19相关的血糖异常患者的炎症和器官损伤标志物增加,临床结局更差。感染解决后,血糖异常的患病率恢复到入院前的水平。

由此可见,COVID-19相关的血糖异常不太可能成为一个持续的公共卫生问题。关于COVID-19肺炎后糖尿病风险的说法应谨慎解释。

原始出处:

Andrea Laurenzi.et al.No evidence of long-term disruption of glycometabolic control after SARS-CoV-2 infection.JCEM.2021.https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab792/6414404

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    2021-11-09 hukaixun
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    2021-12-29 仁者大医
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    2022-01-16 achengzhao
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    2021-11-03 小刀医生