Stroke:卒中前残障可预测不良卒中结局

2019-12-17 xing.T MedSci原创

由此可见,通过mRS评估的卒中前残疾个体,卒中后不良后果的风险显著增加,超急性卒中单元的住院时间更长,出院时需要更高等级的护理水平。

关于卒中前残疾对卒中预后有何影响的数据至今为止仍然缺乏。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在评估卒中前残疾与卒中后住院结局之间的关系。

研究人员分析了从前哨卒中国家审计计划中前瞻性收集的数据。2014年至2016年间,英国4个主要试验地区共收治了1656名男性(平均年龄±SD=73.1±13.2岁)和1653名女性(79.3±13.0岁)需要入住超急性卒中单元的急性卒中患者。研究人员用改良的Rankin量表(mRS)评估卒中前残疾,以针对卒中后不良结局进行检测,并调整了年龄、性别和合并症。

与卒中前mRS得分=0的患者相比,中风前mRS得分=3、4或5的患者就诊时中度到重度卒中调整后风险更高(4.4% vs. 16.7%;比值比[OR]为3.2,[95%CI为2.3-4.6],P<0.001);入院后7天内出现尿路感染或肺炎(9.6% vs. 35.9%;OR为3.7,[95%CI为2.8-4.8],P<0.001)、死亡率(7.2% vs. 37.1%;OR为4.9,[95%CI为3.7-6.5],P<0.001)、在出院后的日常生活活动中需要帮助(12.3% vs. 26.7%;OR为3.1,[95%CI为2.3-4.1],P<0.001)、转诊到新的护理院(2.4% vs. 9.4%;OR为2.1,[95%CI为1.3-3.3],P=0.002)的几率更高。mRS评分=1或2的患者有中等不良结局风险。总体而言,mRS评分=1或2的患者在超急性卒中单元的住院时间延长了5.3天(95%CI为2.8-7.7;P<0.001),mRS评分=3、4或5的患者延长了7.2天(95%CI为4.0-10.5;P<0.001)。

由此可见,通过mRS评估的卒中前残疾个体,卒中后不良后果的风险显著增加,超急性卒中单元的住院时间更长,出院时需要更高等级的护理水平。 

原始出处:

Thang S. Han.et al.Prestroke Disability Predicts Adverse Poststroke Outcome A Registry-Based Prospective Cohort Study of Acute Stroke.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027740

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1755710, encodeId=586e1e557100a, content=<a href='/topic/show?id=2755204905c' target=_blank style='color:#2F92EE;'>#不良卒中结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20490, encryptionId=2755204905c, topicName=不良卒中结局)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3af637003960, createdName=s_pl2020, createdTime=Wed May 27 17:18:00 CST 2020, time=2020-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981129, encodeId=c60619811292a, content=<a href='/topic/show?id=a4833601230' target=_blank style='color:#2F92EE;'>#卒中前残障#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36012, encryptionId=a4833601230, topicName=卒中前残障)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Sun Sep 06 12:18:00 CST 2020, time=2020-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026516, encodeId=d26d1026516ea, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Wed Dec 18 01:18:00 CST 2019, time=2019-12-18, status=1, ipAttribution=)]
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    2019-12-18 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

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