J Hypertens:早年经历了中国饥荒会改变高血压和心血管疾病之间相关性!

2017-08-13 xing.T MedSci原创

由此可见,早年经历中国饥荒加剧了高血压和心血管疾病之间的相关性,特别是在妇女和城市居民或那些肥胖患者中。

研究表明早年经历饥荒可能会增加成年期患心血管疾病、高血压糖尿病的风险。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员旨在评估经历了中国大饥荒(1959年-1961年)是否会改变高血压和心血管疾病之间的关联。

研究人员分析了5772名来自于中国健康与养老纵向研究的出生于1954年至1964年之间的成年人数据。心血管疾病是基于自我报告的医生诊断的心脏问题(心脏病发作、冠心病、心绞痛、充血性心力衰竭或其他心脏问题)和卒中

总体而言,高血压与心血管疾病的风险增加一倍相关(比值比为1.97,1.56-2.48,P<0.001)。研究人员发现高血压和经历饥荒对心血管疾病有显著的交互作用(P=0.04)。对于童年晚期、童年中期、童年早期、胎儿和非经历饥荒组的成人高血压对心血管疾病的比值比分别为:1.69[95%置信区间(CI)为1.06-2.72,P=0.03]、2.35(95%CI为1.44-3.83,P=0.001)、2.48(95%CI为1.49-4.11,P<0.001)、3.35(95%CI为1.54-7.27,P=0.002)和1.40(95%CI为0.82-2.38,P=0.215)。在饥饿人群中高血压和心血管病之间的风险梯度主要见于女性、生活在城市地区和肥胖的人群中。

由此可见,早年经历中国饥荒加剧了高血压和心血管疾病之间的相关性,特别是在妇女和城市居民或那些肥胖患者中。

原始出处:

Shi, Zumin,et al. Early life exposure to Chinese famine modifies the association between hypertension and cardiovascular disease.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/publishahead/Early_life_exposure_to_Chinese_famine_modifies_the.97660.aspx

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-27 虈亣靌

    继续学习中谢谢

    0

  4. 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href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Aug 15 06:00:00 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233576, encodeId=18c12335e62b, content=学了。。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Mon Aug 14 21:47:35 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-26 kalery

    好文章学习了

    0

  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-21 虈亣靌

    谢谢分享.学习了很好!

    0

  6. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-10-21 feather89
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href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Aug 15 06:00:00 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233576, encodeId=18c12335e62b, content=学了。。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Mon Aug 14 21:47:35 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-16 ylzr123

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

  8. 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  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-14 135****7952平儿

    学了。。。。。。。。。

    0

  10. 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href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Aug 15 06:00:00 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233576, encodeId=18c12335e62b, content=学了。。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Mon Aug 14 21:47:35 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233447, encodeId=a72423344e04, content=谢谢分享,学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Aug 14 10:13:32 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-14 明天会更好!

    谢谢分享,学习了很好!

    0

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