Int Arch Allergy Immunol:成年人过敏性鼻炎中,白藜芦醇初级临床效果评估

2018-03-24 AlexYang MedSci原创

白藜芦醇是一种天然的、非黄酮类多酚物质,具有抗炎症活性。之前有报道指出,白藜芦醇与羧甲基-β-葡聚糖一起使用能够在儿童过敏性鼻炎(AR)中减少鼻部症状。最近,有研究人员调查了白藜芦醇在患有AR的成年人中的治疗效果。研究人员进行了一个安慰剂对照、双盲研究。研究包括了151名(年龄18-60岁)患有重度永久性AR的成年人,并将他们分成安慰剂处理组(n=50)和布地奈德处理组(n=50)以及一个白藜芦醇

白藜芦醇是一种天然的、非黄酮类多酚物质,具有抗炎症活性。之前有报道指出,白藜芦醇与羧甲基-β-葡聚糖一起使用能够在儿童过敏性鼻炎(AR)中减少鼻部症状。最近,有研究人员调查了白藜芦醇在患有AR的成年人中的治疗效果。

研究人员进行了一个安慰剂对照、双盲研究。研究包括了151名(年龄18-60岁)患有重度永久性AR的成年人,并将他们分成安慰剂处理组(n=50)和布地奈德处理组(n=50)以及一个白藜芦醇处理组(n=51)。研究发现,与安慰剂处理组相比,使用白藜芦醇或者布地奈德处理的成年人鼻部症状显著减少。白藜芦醇治疗能够显著的减少血液中IgE,、IL-4、 TNF-α和嗜酸性细胞的水平。另外,白藜芦醇治疗还具有提高患有AR成年人生活质量的作用。

最后,研究人员指出,他们的初始结果表明了鼻内使用白藜芦醇能够显著的改善患有过敏性鼻炎成年人的鼻部症状。

原始出处:

Lv C, Zhang Y, Shen L et al. Preliminary Clinical Effect Evaluation of Resveratrol in Adults with Allergic Rhinitis. Int Arch Allergy Immunol l. 14 Mar 2018.

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    2018-03-26 膀胱癌
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    2018-03-25 为你把脉

    滚滚滚还好还好哈哈哈

    0

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    2018-03-24 为你把脉

    v哈哈哈还好还好哈

    0

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