JAMA Cardiol:有氧运动训练可有效降低顽固性高血压患者的动态血压

2021-10-06 Nebula MedSci原创

12周的有氧运动训练可降低顽固性高血压患者的24小时和日间动态血压以及办公室收缩压

迄今为止,顽固性高血压仍是一个临床挑战,尚没有明确的解决方案。有限的证据表明,运动可以降低顽固性高血压患者的血压(BP)

该研究旨在确定有氧运动训练干预是否可降低顽固性高血压患者的动态血压。

这是一项于2017年3月至2019年12月在葡萄牙的两家医院中心开展的前瞻性、单盲的随机临床试验,共招募了60位40-75岁的确诊的顽固性高血压患者。受试患者被1:1随机分至两组,接受12周的中等强度有氧运动训练计划(训练组)或常规护理对照组。主要终点是与基线相比的24小时动态收缩压变化。次要终点包括日间和夜间动态血压、办公室血压和心肺适应能力。

共有53位患者完成了该研究,训练组26位,对照组27位。其中24位(45%)是女性,平均年龄为60.1岁。

两组患者的动态血压变化

与对照组相比,训练组受试者的24小时动态血压降低了7.1mmHg(95% CI -12.8~-1.4; p=0.02)。此外,训练组的24小时动态舒张压(-5.1mmHg; 95% CI -7.9~-2.3; p=0.001)、日间收缩压(-8.4mmHg; 95% CI -14.3~-2.5; p=0.006)和日间舒张压(-5.7mmHg; 95% CI -9.0~-2.4; p=0.001)均较对照组明显降低。而且,训练组的办公室收缩压(-10.0mmHg; 95% CI -17.6~-2.5; p=0.01)和心肺适应能力均较对照组有所改善。

综上所述,12周的有氧运动训练可降低顽固性高血压患者的24小时和日间动态血压以及办公室收缩压。该研究为临床医生提供了证据,以中等强度的有氧运动作为这类患者的标准辅助治疗。

原始出处:

Lopes S, Mesquita-Bastos J, Garcia C, et al. Effect of Exercise Training on Ambulatory Blood Pressure Among Patients With Resistant Hypertension: A Randomized Clinical Trial. JAMA Cardiol. Published online August 04, 2021. doi:10.1001/jamacardio.2021.2735

 

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    2021-10-07 老龙一点

    学习

    0

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    2021-10-07 谭桂峰

    运动可以降低顽固性高血压患者的血压。

    0

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    2021-10-07 仁术2021

    不错学习了

    0

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