Lancet Infect Dis:加蓬地区罗阿丝虫病负担研究

2020-06-23 网络 网络

罗阿丝虫病具有眼部虫体移行的病理特征,在非洲地区的发病率很高,已经对当地居民的健康和生活质量造成了严重影响

罗阿丝虫病是在撒哈拉以南非洲高度流行的蠕虫感染,近日研究人员使用残疾调整寿命年(DALYs)对加蓬地区由罗阿丝虫病引起的疾病总负担进行前瞻性量化。
 
研究人员在2017-2018年对加蓬农村地区进行了一项横断面调查。参与者接受了关于罗阿丝虫病的诊断性检查,并接受了症状标准化问卷调查。报告虫体在眼部移行或携带Loa-Loa微丝蚴的参与者被定义为罗阿丝虫病阳性。对加蓬农村人口中与罗阿丝虫病相关疾病的DALY进行了估计。
 
2017年9月1日至2018年5月31日期间,对居住在加蓬38个村庄的1235名参与者进行了筛查。1232名符合条件的参与者中有626人(50.8%)患有罗阿丝虫病。1232名参与者中有520人(42.2%)报告了眼部虫体移行。509名眼部虫体移行患者中,478名(93.9%)报告有相关疼痛, 397名(78.6%)报告有视力障碍。校正年龄和性别后,罗阿丝虫病与多种症状显著相关,包括短暂性疼痛性水肿(校正比值比1.76)和关节痛(1.30)。在加蓬农村,每10万人中有412.9人因罗阿丝虫病DALYs受到影响。
 
罗阿丝虫病具有眼部虫体移行的病理特征,在非洲地区的发病率很高,已经对当地居民的健康和生活质量造成了严重影响。
 
原始出处:
 
Luzia Veletzky et al. Burden of disease in Gabon caused by loiasis: a cross-sectional survey.Lancet Infect Dis. June 22,2020.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=2013409, encodeId=21392013409b4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Jul 14 10:05:41 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077474, encodeId=a71e20e7474bc, content=<a href='/topic/show?id=fd8c21045f7' target=_blank style='color:#2F92EE;'>#丝虫病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21045, encryptionId=fd8c21045f7, topicName=丝虫病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Feb 14 07:05:41 CST 2021, time=2021-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813700, encodeId=6d55813e0006, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 07:53:56 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033855, encodeId=c83d103385558, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Tue Jun 23 22:05:41 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799487, encodeId=5856e994879e, content=<a href='/topic/show?id=99fd46525ad' target=_blank style='color:#2F92EE;'>#寄生虫#</a>寄生虫是一个小学科,经常被忽视,事实上危害依然很大。因此,这个小学科同样可以发顶级刊物, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46525, encryptionId=99fd46525ad, topicName=寄生虫)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Jun 23 21:03:39 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830711, encodeId=17321830e1122, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Dec 25 00:05:41 CST 2020, time=2020-12-25, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2013409, encodeId=21392013409b4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Jul 14 10:05:41 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077474, encodeId=a71e20e7474bc, content=<a href='/topic/show?id=fd8c21045f7' target=_blank style='color:#2F92EE;'>#丝虫病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21045, encryptionId=fd8c21045f7, topicName=丝虫病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Feb 14 07:05:41 CST 2021, time=2021-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813700, encodeId=6d55813e0006, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 07:53:56 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033855, encodeId=c83d103385558, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Tue Jun 23 22:05:41 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799487, encodeId=5856e994879e, content=<a href='/topic/show?id=99fd46525ad' target=_blank style='color:#2F92EE;'>#寄生虫#</a>寄生虫是一个小学科,经常被忽视,事实上危害依然很大。因此,这个小学科同样可以发顶级刊物, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46525, encryptionId=99fd46525ad, topicName=寄生虫)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Jun 23 21:03:39 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830711, encodeId=17321830e1122, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Dec 25 00:05:41 CST 2020, time=2020-12-25, status=1, ipAttribution=)]
    2020-08-27 14818eb4m67暂无昵称

    学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2013409, encodeId=21392013409b4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Jul 14 10:05:41 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077474, encodeId=a71e20e7474bc, content=<a href='/topic/show?id=fd8c21045f7' target=_blank style='color:#2F92EE;'>#丝虫病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21045, encryptionId=fd8c21045f7, topicName=丝虫病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Feb 14 07:05:41 CST 2021, time=2021-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813700, encodeId=6d55813e0006, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 07:53:56 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033855, encodeId=c83d103385558, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Tue Jun 23 22:05:41 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799487, encodeId=5856e994879e, content=<a href='/topic/show?id=99fd46525ad' target=_blank style='color:#2F92EE;'>#寄生虫#</a>寄生虫是一个小学科,经常被忽视,事实上危害依然很大。因此,这个小学科同样可以发顶级刊物, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46525, encryptionId=99fd46525ad, topicName=寄生虫)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Jun 23 21:03:39 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830711, encodeId=17321830e1122, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Dec 25 00:05:41 CST 2020, time=2020-12-25, status=1, ipAttribution=)]
    2020-06-23 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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    2020-06-23 lovetcm

    #寄生虫#寄生虫是一个小学科,经常被忽视,事实上危害依然很大。因此,这个小学科同样可以发顶级刊物

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2013409, encodeId=21392013409b4, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Jul 14 10:05:41 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077474, encodeId=a71e20e7474bc, content=<a href='/topic/show?id=fd8c21045f7' target=_blank style='color:#2F92EE;'>#丝虫病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21045, encryptionId=fd8c21045f7, topicName=丝虫病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Feb 14 07:05:41 CST 2021, time=2021-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813700, encodeId=6d55813e0006, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 07:53:56 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033855, encodeId=c83d103385558, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Tue Jun 23 22:05:41 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799487, encodeId=5856e994879e, content=<a href='/topic/show?id=99fd46525ad' target=_blank style='color:#2F92EE;'>#寄生虫#</a>寄生虫是一个小学科,经常被忽视,事实上危害依然很大。因此,这个小学科同样可以发顶级刊物, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46525, encryptionId=99fd46525ad, topicName=寄生虫)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Jun 23 21:03:39 CST 2020, time=2020-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830711, encodeId=17321830e1122, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Dec 25 00:05:41 CST 2020, time=2020-12-25, status=1, ipAttribution=)]
    2020-12-25 howi