Stroke:无创脑血氧饱和度检测缺血性脑卒中患者中的前循环大动脉闭塞患者!

2018-01-11 xing.T MedSci原创

由此可见,无创脑血氧检测可以帮助识别缺血性脑卒中患者中的LAO患者,特别是与简单的临床评分系统进行结合时。

缺血性卒中被转送至血管内卒中治疗中心时,需要对缺血性卒中患者中的大动脉闭塞(LAO)患者进行识别和分类。为了改善分类效能进行无创性LAO检测尤为重要。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在评估使用无创性脑血氧饱和度检测缺血性脑卒中患者中前循环大动脉闭塞患者。

该前瞻性研究旨在明确无创脑血氧饱和度是否可以检测急性脑卒中患者中的前循环LAO患者。研究人员比较了LAO患者和对照者大脑半球间的ΔBrSO2。

在LAO卒中患者中,平均大脑半球间ΔBrSO2为-8.3±5.8%(n=19),相比于小动脉卒中患者为0.4±5.8%(n=17),出血性卒中患者为0.4±6%(n=14),以及无卒中患者为0.2±7.5%(n=19)(P<0.001)。血管内脑卒中治疗可以降低大多数LAO患者大脑半球间ΔBrSO2(16/19)。将大脑半球间ΔBrSO2临界值定为-3%时,其区分LAO的敏感性为84%,特异性为70%。将G-FAST临床评分(凝视-脸-手臂-语音-时间)加入到ΔBrSO2指标可维持敏感性为84%,特异性变为90%。

由此可见,无创脑血氧检测可以帮助识别缺血性脑卒中患者中的LAO患者,特别是与简单的临床评分系统进行结合时。

原始出处:

Alexander C. Flint, et al. Detection of Anterior Circulation Large Artery Occlusion in Ischemic Stroke Using Noninvasive Cerebral Oximetry.Stroke. 2018. https://doi.org/10.1161/STROKEAHA.117.020140

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  5. 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  8. 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  9. 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    2018-01-12 lqvr

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