Rheumatology:扩展超声检查发现巨细胞动脉炎患者更大血管受累

2022-08-29 紫菀款冬 MedSci原创

比较有限的和更广泛的超声检查(前内侧超声,A2超声)检测新诊断的巨细胞动脉炎(GCA)患者的大血管(LV)受累情况。

目的:比较有限的和更广泛的超声检查(前内侧超声,A2超声)检测新诊断巨细胞动脉炎(GCA)患者的血管(LV)受累情况。

方法:在确诊时纳入新发GCA患者。除颞动脉超声外,所有患者均使用有限超声(腋窝动脉的超声成像)扩展A2超声方法(包括颈动脉、椎动脉、锁骨下动脉和腋窝近端动脉)进行检查。

结果:该研究共纳入133名患者。根据1990年美国风湿病学会(ACR)GCA分类标准的扩展,所有患者均符合标准,诊断时超声检查呈阳性。

133例GCA患者中有93例(70.0%)在扩展A2超声检查时有LV受累,而有限超声检查仅56例(42.1%)(p<0001)。

12名患者(9.0%)的椎动脉血管炎是唯一LV受累的疾病。

如果仅进行有限的超声检查,5名患者(3.8%)可能会被误诊为GCA。

40名患者(30.0%)患有孤立性颅骨GCA(c-GCA),21名患者(15.8%)患有孤立的大血管GCA(LV-GCA),72名患者(54.1%)患有混合性GCA。

结论:与有限超声方法相比,扩展A2超声检查可识别更多的LV受累患者。然而,扩展的A2超声需要更高水平的专业知识和高端设备,应由经过充分培训的超声医师进行。

 

文献来源:

Bull Haaversen AC, Brekke LK, Kermani TA, et al. Extended ultrasound examination identifies more large vessel involvement in patients with giant cell arteritis [published online ahead of print, 2022 Aug 23]. Rheumatology (Oxford). 2022;keac478. doi:10.1093/rheumatology/keac478

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    2022-11-07 kkunny
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    2023-07-22 xsm927
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    2022-08-27 wwzzly

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