Diabetes Care:青少年和年轻成人糖尿病患者的血糖控制趋势

2022-01-16 MedSci原创 MedSci原创

尽管糖尿病检测技术、药物和更积极的降血糖目标的取得了很大进步,但与早期队列相比,当前许多YYA不太可能达到所需的血糖控制水平。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在描述青年发病的糖尿病青少年和年轻成人(YYA)血糖控制的时间趋势和相关性。

该研究纳入了来自糖尿病年轻人研究的6369名1型或2型糖尿病患者。参与者就诊数据分为2002-2007年、2008-2013年和2014-2019年的时间段,糖尿病病程分为1-4、5-9和≥10年,以及1-9、10-14、15-19、20-24和≥25岁的年龄组。

研究人员采用多变量回归模型评估了不同糖尿病类型的血红蛋白A1c(HbA1c)随时间的差异。模型针对地点、年龄、性别、种族/民族、家庭收入、健康保险状况、胰岛素治疗方案和糖尿病病程进行了调整,并对每个糖尿病病程和年龄组进行了总体和分层分析。

2014-2019年1型糖尿病YYA队列的调整后平均HbA1c为8.8±0.04%。2014-2019年队列中10-14岁、15-19岁和20-24岁年龄组1型糖尿病YYA的血糖控制比2002-2007年队列差。种族/民族、家庭收入和治疗方案预测了2014-2019年期间队列中1型糖尿病参与者的血糖控制差异。2014-2019年期间2型糖尿病YYA的调整后平均HbA1c为8.6±0.12%。与2008-2013年队列相比,年龄≥25岁的2型糖尿病参与者的血糖控制较差。只有治疗方案与2型糖尿病参与者的血糖控制差异有关。

由此可见,尽管糖尿病检测技术、药物和更积极的降血糖目标的取得了很大进步,但与早期队列相比,当前许多YYA不太可能达到所需的血糖控制水平。

原始出处:
 
Faisal S. Malik.et al.Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study.Diabetes care.2022.https://diabetesjournals.org/care/online-ahead-of-print

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    2022-02-11 王守伟

    不错。

    0

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    2022-01-17 ms6000001120242895

    学习啦

    0

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    2022-01-17 ms5000001321649639

    学习

    0

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