Clinical Gastroenterology H: 肥胖与女性结肠憩室的关系

2019-12-27 不详 MedSci原创

有研究表明,肥胖与结肠憩室病风险增加有关。但是这种关联的证据是有限的。因此,本项研究旨在评估肥胖是否与结肠憩室有关。

背景与目标
有研究表明,肥胖与结肠憩室病风险增加有关。但是这种关联的证据是有限的。因此,本项研究旨在评估肥胖是否与结肠憩室有关。

方法
研究人员分析了2013年至2015年间总共623例接受结肠镜检查的患者的前瞻性研究数据;结肠镜检查包括憩室检查。在手术当天进行身体测量。使用修正的Poisson回归进行多变量分析,以估计患病率(PR)和95%CI,同时调整混杂变量。所有分析均按性别分层。

结果
在男性中,肥胖与憩室之间没有任何联系。调整后,与体重指数正常(BMI 18.5-24.9)的女性相比,肥胖指数(BMI≥30)的女性发生憩室病的风险增加(PR,1.48; 95%CI,1.08-2.04)。对于超过5个憩室,这种关联的强度更大(PR,2.05; 95%CI,1.23-3.40)。妇女中度肥胖与憩室病之间无显着相关性。按性别分层,女性结肠结肠憩室的发生率明显低于51岁之前的男性(29% VS 45%,P = .06)。老年人群中憩室病的患病率在性别上没有差异。

结论
本项研究发现肥胖(BMI≥30)显着增加了女性而非男性的结肠憩室病风险。与同龄男性相比,绝经前女性的结肠憩室病患病率较低。

原始出处:
Anne F. Peery. Et al. Association of Obesity With Colonic Diverticulosis in Women. Clinical Gastroenterology H. 2019.

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    2020-10-27 许安
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    2020-01-01 一天没事干

    很好的学习机会

    0

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    2019-12-29 zll0628
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    2019-12-29 zutt
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