BMJ Open:男性易发生不稳定型心绞痛

2015-10-20 Mechront 译 MedSci原创

不稳定型心绞痛,是介于劳累性稳定型心绞痛与急性心肌梗死和猝死之间的临床表现。主要包括初发心绞痛、恶化劳力性心绞痛、静息心绞痛伴心电图缺血改变和心肌梗死后早期心绞痛。其特征是心绞痛症状进行性增加,新发作的休息或夜间性心绞痛或出现心绞痛持续时间延长。研究者在芬兰进行了一项基于人群的回顾性研究,探究因不稳定型心绞痛(UAP)的住院率的性别差异和年龄差异。该研究纳入了2000年5月-2009年10月间、≥

不稳定型心绞痛,是介于劳累性稳定型心绞痛与急性心肌梗死和猝死之间的临床表现。主要包括初发心绞痛、恶化劳力性心绞痛、静息心绞痛伴心电图缺血改变和心肌梗死后早期心绞痛。其特征是心绞痛症状进行性增加,新发作的休息或夜间性心绞痛或出现心绞痛持续时间延长。

研究者在芬兰进行了一项基于人群的回顾性研究,探究因不稳定型心绞痛(UAP)的住院率的性别差异和年龄差异。该研究纳入了2000年5月-2009年10月间、≥30岁、因初次诊断UAP而入院的27282名患者。其中 61.9% 为男性, 38.1% 为女性。

校正年龄后,“男性”会增加UAP风险(RR 1.85;CI 1.61 to 2.14;p<0.0001)。整个研究期间,研究者观察到UAP的整体发病率为92.8/100 000人年(CI 91.8 - 93.9)。UAP发病率随年龄增长,30-34岁人群发病率为1.3/100 000,75-84岁人群的发病率为268.0/100 000。

在普通人群中,因UAP住院的事件中,男性风险是女性的2.4倍(ncidence rate ratio 2.39; CI 2.24 - 2.56; p<0.0001)。在每个年龄组都可以发现UAP发病的性别差异。

因UAP导致的急性冠脉综合征而住院的占22.4%,导致心血管疾病而住院的有4.7%。对于男性病人,UAP更容易导致心血管疾病(RR=1.25; CI 1.21 - 1.30, p<0.0001),但是在急性冠脉综合征这一块,性别间的差异不大,无统计学意义。

随着每个研究年的增长,一般人群中UAP住院率按约8%的速度下降,不管男性女性,还是少年老年,该下降是显著的。

研究结果表明,普通人群里男性因不稳定型心绞痛(UAP)住院的风险是女性的2.4倍。对于芬兰人群,UAP住院率呈下降趋势。

原始出处:

Kytö V, Sipilä J, Rautava P,et al.Gender-specific and age-specific differences in unstable angina pectoris admissions: a population-based registry study in Finland.BMJ Open. 2015 Oct 15;5(10):e009025.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1803344, encodeId=2de61803344a5, content=<a href='/topic/show?id=8b44e528972' target=_blank style='color:#2F92EE;'>#稳定型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75289, encryptionId=8b44e528972, topicName=稳定型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Jun 26 17:34:00 CST 2016, time=2016-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847726, encodeId=43e2184e7265a, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 26 22:34:00 CST 2016, time=2016-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981735, encodeId=b7441981e35ad, content=<a href='/topic/show?id=e398204493e' target=_blank style='color:#2F92EE;'>#不稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20449, encryptionId=e398204493e, topicName=不稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sun May 22 19:34:00 CST 2016, time=2016-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725904, encodeId=7d281e259045d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Jul 30 01:34:00 CST 2016, time=2016-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568884, encodeId=43d11568884d7, content=<a href='/topic/show?id=7de4e529403' target=_blank style='color:#2F92EE;'>#稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75294, encryptionId=7de4e529403, topicName=稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615115475291, createdName=lizhou0209, createdTime=Thu Oct 22 14:34:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1803344, encodeId=2de61803344a5, content=<a href='/topic/show?id=8b44e528972' target=_blank style='color:#2F92EE;'>#稳定型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75289, encryptionId=8b44e528972, topicName=稳定型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Jun 26 17:34:00 CST 2016, time=2016-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847726, encodeId=43e2184e7265a, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 26 22:34:00 CST 2016, time=2016-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981735, encodeId=b7441981e35ad, content=<a href='/topic/show?id=e398204493e' target=_blank style='color:#2F92EE;'>#不稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20449, encryptionId=e398204493e, topicName=不稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sun May 22 19:34:00 CST 2016, time=2016-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725904, encodeId=7d281e259045d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Jul 30 01:34:00 CST 2016, time=2016-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568884, encodeId=43d11568884d7, content=<a href='/topic/show?id=7de4e529403' target=_blank style='color:#2F92EE;'>#稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75294, encryptionId=7de4e529403, topicName=稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615115475291, createdName=lizhou0209, createdTime=Thu Oct 22 14:34:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
    2016-07-26 gaoxiaoe
  3. [GetPortalCommentsPageByObjectIdResponse(id=1803344, encodeId=2de61803344a5, content=<a href='/topic/show?id=8b44e528972' target=_blank style='color:#2F92EE;'>#稳定型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75289, encryptionId=8b44e528972, topicName=稳定型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Jun 26 17:34:00 CST 2016, time=2016-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847726, encodeId=43e2184e7265a, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 26 22:34:00 CST 2016, time=2016-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981735, encodeId=b7441981e35ad, content=<a href='/topic/show?id=e398204493e' target=_blank style='color:#2F92EE;'>#不稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20449, encryptionId=e398204493e, topicName=不稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sun May 22 19:34:00 CST 2016, time=2016-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725904, encodeId=7d281e259045d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Jul 30 01:34:00 CST 2016, time=2016-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568884, encodeId=43d11568884d7, content=<a href='/topic/show?id=7de4e529403' target=_blank style='color:#2F92EE;'>#稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75294, encryptionId=7de4e529403, topicName=稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615115475291, createdName=lizhou0209, createdTime=Thu Oct 22 14:34:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1803344, encodeId=2de61803344a5, content=<a href='/topic/show?id=8b44e528972' target=_blank style='color:#2F92EE;'>#稳定型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75289, encryptionId=8b44e528972, topicName=稳定型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Jun 26 17:34:00 CST 2016, time=2016-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847726, encodeId=43e2184e7265a, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 26 22:34:00 CST 2016, time=2016-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981735, encodeId=b7441981e35ad, content=<a href='/topic/show?id=e398204493e' target=_blank style='color:#2F92EE;'>#不稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20449, encryptionId=e398204493e, topicName=不稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sun May 22 19:34:00 CST 2016, time=2016-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725904, encodeId=7d281e259045d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Jul 30 01:34:00 CST 2016, time=2016-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568884, encodeId=43d11568884d7, content=<a href='/topic/show?id=7de4e529403' target=_blank style='color:#2F92EE;'>#稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75294, encryptionId=7de4e529403, topicName=稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615115475291, createdName=lizhou0209, createdTime=Thu Oct 22 14:34:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
    2016-07-30 feather89
  5. [GetPortalCommentsPageByObjectIdResponse(id=1803344, encodeId=2de61803344a5, content=<a href='/topic/show?id=8b44e528972' target=_blank style='color:#2F92EE;'>#稳定型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75289, encryptionId=8b44e528972, topicName=稳定型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Jun 26 17:34:00 CST 2016, time=2016-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847726, encodeId=43e2184e7265a, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 26 22:34:00 CST 2016, time=2016-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981735, encodeId=b7441981e35ad, content=<a href='/topic/show?id=e398204493e' target=_blank style='color:#2F92EE;'>#不稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20449, encryptionId=e398204493e, topicName=不稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sun May 22 19:34:00 CST 2016, time=2016-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725904, encodeId=7d281e259045d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Jul 30 01:34:00 CST 2016, time=2016-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568884, encodeId=43d11568884d7, content=<a href='/topic/show?id=7de4e529403' target=_blank style='color:#2F92EE;'>#稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75294, encryptionId=7de4e529403, topicName=稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615115475291, createdName=lizhou0209, createdTime=Thu Oct 22 14:34:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]

相关资讯

TCT2014:高危患者PCI术后30天内支架内血栓形成风险增加

9月13~17日,2014年经导管心血管治疗大会在美国华盛顿正如火如荼地召开。中国众多心血管专家也在TCT大会现场以主持会议、口头报告、病例展示等多种形式与国际同仁进行着学术交流。河北医科大学第二医院傅向华教授团队特别从会议现场发来报道,以期第一时间与国内心血管医生共享学术进展。 在TCT 2014的口头发言中报告了ADAPT-DES试验结果,结果发现,与稳定型冠心病患者相比,急性冠状动脉综合征