Crit Care:重症患者中心静脉压升高与死亡率增加和急性肾损伤相关

2020-03-06 xing.T MedSci原创

由此可见,CVP升高与重症监护病房成年重症患者死亡和AKI风险增加有关。

在重症成年患者中,中心静脉压(CVP)与死亡率和急性肾损伤(AKI)的关系仍不清楚。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,研究人员进行了荟萃分析,以明确成年危重患者CVP升高是否与增加的死亡率和AKI有关。

研究人员对PubMed和Embase进行了检索,时间截止至2019年6月,以确定入住重症监护病房的成年危重患者CVP与死亡率和/或AKI之间关系的研究。研究人员使用随机效应模型计算了总的比值比(OR)和95%CI。

该分析纳入了十五项危重患者(主要是败血症)的队列研究。对于二分类数据,CVP升高与死亡(3项研究;969名参与者; OR为1.65;95%CI为1.19-2.29)和AKI(2项研究;689名参与者;OR为2.09; 95%CI为1.39-3.14)风险增加。对于连续数据,较高的CVP与较高的死亡(5项研究;7837名参与者; OR为1.10; 95%CI为1.03-1.17)和AKI(6项研究; 5446名参与者;OR为1.14;95%CI为1.06-1.23)风险相关。此外,CVP每增加1mmHg,AKI的几率就会增加6%(4项研究;5150名参与者; OR为1.06;95%CI为1.01-1.12)。对仅限于败血症患者开展进一步分析得出了一致的结果。

由此可见,CVP升高与重症监护病房成年重症患者死亡和AKI风险增加有关。

原始出处:

Chuan-Yu Chen.et al.Elevated central venous pressure is associated with increased mortality and acute kidney injury in critically ill patients: a meta-analysis.Critical Care.2020.https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-2770-5

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1698054, encodeId=19031698054e5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Fri Apr 10 11:29:00 CST 2020, time=2020-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715614, encodeId=122e1e15614e2, content=<a href='/topic/show?id=83622218699' target=_blank style='color:#2F92EE;'>#中心静脉压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22186, encryptionId=83622218699, topicName=中心静脉压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5631964592, createdName=ms4657536712156177, createdTime=Mon Feb 01 11:29:00 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796996, encodeId=31a11e96996ea, content=<a href='/topic/show?id=5a6e221853a' target=_blank style='color:#2F92EE;'>#中心静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22185, encryptionId=5a6e221853a, topicName=中心静脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Jul 24 19:29:00 CST 2020, time=2020-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284091, encodeId=544112840911f, content=<a href='/topic/show?id=cdb79594643' target=_blank style='color:#2F92EE;'>#重症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95946, encryptionId=cdb79594643, topicName=重症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c3a189, createdName=longqijun248, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397924, encodeId=6c0a139e924f2, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=)]
    2020-04-10 fusion
  2. [GetPortalCommentsPageByObjectIdResponse(id=1698054, encodeId=19031698054e5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Fri Apr 10 11:29:00 CST 2020, time=2020-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715614, encodeId=122e1e15614e2, content=<a href='/topic/show?id=83622218699' target=_blank style='color:#2F92EE;'>#中心静脉压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22186, encryptionId=83622218699, topicName=中心静脉压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5631964592, createdName=ms4657536712156177, createdTime=Mon Feb 01 11:29:00 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796996, encodeId=31a11e96996ea, content=<a href='/topic/show?id=5a6e221853a' target=_blank style='color:#2F92EE;'>#中心静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22185, encryptionId=5a6e221853a, topicName=中心静脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Jul 24 19:29:00 CST 2020, time=2020-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284091, encodeId=544112840911f, content=<a href='/topic/show?id=cdb79594643' target=_blank style='color:#2F92EE;'>#重症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95946, encryptionId=cdb79594643, topicName=重症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c3a189, createdName=longqijun248, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397924, encodeId=6c0a139e924f2, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1698054, encodeId=19031698054e5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Fri Apr 10 11:29:00 CST 2020, time=2020-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715614, encodeId=122e1e15614e2, content=<a href='/topic/show?id=83622218699' target=_blank style='color:#2F92EE;'>#中心静脉压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22186, encryptionId=83622218699, topicName=中心静脉压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5631964592, createdName=ms4657536712156177, createdTime=Mon Feb 01 11:29:00 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796996, encodeId=31a11e96996ea, content=<a href='/topic/show?id=5a6e221853a' target=_blank style='color:#2F92EE;'>#中心静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22185, encryptionId=5a6e221853a, topicName=中心静脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Jul 24 19:29:00 CST 2020, time=2020-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284091, encodeId=544112840911f, content=<a href='/topic/show?id=cdb79594643' target=_blank style='color:#2F92EE;'>#重症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95946, encryptionId=cdb79594643, topicName=重症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c3a189, createdName=longqijun248, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397924, encodeId=6c0a139e924f2, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1698054, encodeId=19031698054e5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Fri Apr 10 11:29:00 CST 2020, time=2020-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715614, encodeId=122e1e15614e2, content=<a href='/topic/show?id=83622218699' target=_blank style='color:#2F92EE;'>#中心静脉压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22186, encryptionId=83622218699, topicName=中心静脉压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5631964592, createdName=ms4657536712156177, createdTime=Mon Feb 01 11:29:00 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796996, encodeId=31a11e96996ea, content=<a href='/topic/show?id=5a6e221853a' target=_blank style='color:#2F92EE;'>#中心静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22185, encryptionId=5a6e221853a, topicName=中心静脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Jul 24 19:29:00 CST 2020, time=2020-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284091, encodeId=544112840911f, content=<a href='/topic/show?id=cdb79594643' target=_blank style='color:#2F92EE;'>#重症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95946, encryptionId=cdb79594643, topicName=重症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c3a189, createdName=longqijun248, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397924, encodeId=6c0a139e924f2, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1698054, encodeId=19031698054e5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Fri Apr 10 11:29:00 CST 2020, time=2020-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715614, encodeId=122e1e15614e2, content=<a href='/topic/show?id=83622218699' target=_blank style='color:#2F92EE;'>#中心静脉压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22186, encryptionId=83622218699, topicName=中心静脉压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5631964592, createdName=ms4657536712156177, createdTime=Mon Feb 01 11:29:00 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796996, encodeId=31a11e96996ea, content=<a href='/topic/show?id=5a6e221853a' target=_blank style='color:#2F92EE;'>#中心静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22185, encryptionId=5a6e221853a, topicName=中心静脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Jul 24 19:29:00 CST 2020, time=2020-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284091, encodeId=544112840911f, content=<a href='/topic/show?id=cdb79594643' target=_blank style='color:#2F92EE;'>#重症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95946, encryptionId=cdb79594643, topicName=重症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c3a189, createdName=longqijun248, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397924, encodeId=6c0a139e924f2, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sun Mar 08 08:29:00 CST 2020, time=2020-03-08, status=1, ipAttribution=)]

相关资讯

JAMA:减少血管紧张素暴露对老年重症患者血管扩张性低血压90天死亡率的影响

通常向重症监护病房(ICU)患者施用升压药以升高血压。平衡血管加压药的风险和益处是一项挑战,特别是在老年患者中。

鄂州:开展多学科讨论,为每位重症患者提供个性化诊疗方案

3月5日下午,湖北省新冠病毒肺炎疫情防控工作指挥部召开第39场新闻发布会,介绍鄂州市疫情防控工作和贵州省对口支援情况。发布会上,有记者提问,集中收治危重病人的鄂州市中心医院在救治方面采取了哪些措施?鄂州市中心医院党委书记、院长刘黎明介绍,鄂州市中心医院作为鄂州市唯一的一家三级甲等医院,被定为鄂州市新冠肺炎危重症定点救治医院,全市所有危重病人和绝大部分重症病人在都在中心医院。 刘黎明说,医

武汉通报肺炎疫情:重症患者11例,已排除多种常见呼吸道疾病

1月3日,武汉市卫健委发布不明原因病毒性肺炎最新通报。目前发现符合不明原因的病毒性肺炎诊断患者44例,其中重症11例。所有病例均在武汉市医疗机构接受隔离治疗,已经追踪到121名密切接触者并行医学观察,密切接触者的追踪工作仍在进行中。已排除流感、禽流感、腺病毒感染等常见呼吸道疾病。全文如下:武汉市卫健委关于不明原因的病毒性肺炎情况通报 2019年12月以来,我委开展呼吸道疾病及相关疾病监测

2020 专家声明:重症患者艰难梭菌感染

艰难梭菌感染(CDI)临床表现严重,本文主要针对重症患者艰难梭菌感染进行概述。主要涉及CDI危重患者的病理生理学,危险因素,诊断以及治疗。

2020 ESICM临床实践指南:非出血性重症患者的输血策略

2020年1月,欧洲危重病医学会(ESICM)发布了非出血性重症患者的输血策略指南,指南共针对非出血性重症患者的输血相关问题提出了16条临床实践建议。

新型冠状病毒感染肺炎重症患者的营养支持及监护建议

新型冠状病毒感染肺炎重症患者的营养不良状态会对其疾病预后产生重要影响.根据相关指南及共识,提出新型冠状病毒感染肺炎重症患者的营养支持及监护建议。(新冠肺炎、新型冠状病毒、冠状病毒、冠状病毒性肺炎、2019冠状病毒病、COVID-19、SARS-CoV-2 、NCP)