Radiology:哪种基底动脉闭塞机械取栓后预后好?

2019-08-14 shaosai MedSci原创

背景:由于基底动脉闭塞(BAO)所致急性脑卒中约占缺血性脑卒中的1%。然而,对于不同病理亚型的BAO脑卒中再通率和治疗结果尚不明确。本研究旨在比较不同BAO亚型经机械取栓后再通率和临床预后的差异。

背景:由于基底动脉闭塞(BAO)所致急性脑卒中约占缺血性脑卒中的1%。然而,对于不同病理亚型的BAO脑卒中再通率和治疗结果尚不明确。本研究旨在比较不同BAO亚型经机械取栓后再通率和临床预后的差异。

本研究纳入了82例急性BAO并行机械取栓的患者进行分析。患者被分为3组:无椎动脉(VA)狭窄性闭塞的栓塞(组1)、合并VA狭窄性闭塞的栓塞(组2)和基底动脉动脉粥样硬化性栓塞(组3)。利用Kruskal-Wallis、Pearson χ2和Fisher精确检验比较两组间临床和造影相关特点、再通率、手术时间和临床预后。

结果为,根据脑卒中机制,组1、组2和组3 BAO发生率分别为n = 34 (41%)、 n = 28 (34%)和n = 20 (24%)。整体上,机械再通率达到78% (64/82),预后良好为37% (30/82)。组1的手术时间要明显短于组2(49 vs 66分钟; P = .01)。组1的血管再通率要明显高于组3((29/34 [85%] vs 11/20 [55%]; P = .01))。组1临床预后要高于组3((18/34 [53%] vs 4/20 [20%]; P = .02)).

本研究表明,根据不同病理学脑卒中机制的基底动脉闭塞预后是不同的,在无椎动脉狭窄性闭塞的栓塞患者的预后和再通率最好。

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