J Dent:不同成分牙膏原位抗菌效果的评估-一项3组临床随机试验的混合分析

2018-07-29 lishiting MedSci原创

研究从3组相似的原位龋交叉试验共同组成的一项混合分析中获得数据,以此来评估如何使用浓度在1400-1450 ppm F之间以及不同研磨系统中的不同氟化物盐和洁齿剂配方组合,并且在某些情况下添加了附加剂卡波姆(Carb)时,会影响牙釉质龋损的再矿化和氟化作用。

研究从3组相似的原位龋交叉试验共同组成的一项混合分析中获得数据,以此来评估如何使用浓度在1400-1450 ppm F之间以及不同研磨系统中的不同氟化物盐和洁齿剂配方组合,并且在某些情况下添加了附加剂卡波姆(Carb)时,会影响牙釉质龋损的再矿化和氟化作用。受试者持续佩戴改良的由两个薄金属网覆盖的部分脱矿人牙釉质样本的局部义齿14天,每天2次用指定的牙膏刷牙:方案1:氟化钠(NaF)/Carb/silica,NaF/silica, NaF+MFP/chalk; 方案2:NaF/Carb/silica, NaF+MFP/dical, 氟化铵(AmF)/silica; 方案3:NaF/Carb/silica, NaF+氟化亚锡(SnF2)/silica/六偏磷酸盐(HMP)。所有研究均包含安慰剂(0ppm F)和/或剂量反应对照(675ppm F as NaF [675F-NaF]) ±Carb。样本通过显微硬度恢复(SMHR)和釉质氟化物摄取(EFU)表面积的百分比进行评估。结果显示,所有1400-1450 ppm F的牙膏除了NaF+SnF2/silica/HMP均比安慰剂组明显提高了

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    2018-07-29 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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