SCI REP:前列腺癌根治术后盆底重建改选什么方法?

2017-06-03 xing.T MedSci原创

由此可见,接受根治性前列腺切除术的患者并且采用后路重建治疗尿失禁出现最少。采用前壁悬吊、前路重建联合后路重建治疗和前壁悬吊联合后路重建治疗在术后没有观察到明显的益处。

根治性前列腺切除术是治疗局限性前列腺癌的金标准。近日,Scientific reports 杂志上发表了一篇荟萃分析文章,研究人员进行了一项荟萃分析旨在评估不同的盆底重建技术对尿失禁的治疗效果。

研究人员对评估盆底重建的疗效的试验进行一个全面的检索,研究人员检索了相关的数据库包括PubMed、EMBASE、Cochrane图书馆、Ovid以及Web of Science 数据库,从文献中得到了相关试验数据。研究人员采用随机效应模型来估计风险比(RRS)这一统计量。

研究人员发现接受后路重建治疗的患者汇总的结果显示完全性尿失禁在拔除导尿管后1-4天、28-42天、90天、180天和360天有所改善。采用前壁悬吊仅改善拔除导尿管后28-42天的完全性尿失禁。前路重建联合后路重建治疗可以改善拔除导尿管后1-4天、90天和180天的尿失禁症状。前壁悬吊联合后路重建治疗不能获得任何改善的益处。并且后路重建治疗改善拔管后7-14天和28-42天的社会性尿失禁症状。前壁悬吊不能获得明显的益处。前路重建联合后路重建治疗可以获得90天和180天更好的结果。

由此可见,接受根治性前列腺切除术的患者并且采用后路重建治疗尿失禁出现最少。采用前壁悬吊、前路重建联合后路重建治疗和前壁悬吊联合后路重建治疗在术后没有观察到明显的益处。

原始出处:

Jianfeng Cui, et al. Pelvic Floor Reconstruction After Radical Prostatectomy: A Systematic Review and Meta-analysis of Different Surgical Techniques. Scientific reports. 2017. https://www.nature.com/articles/s41598-017-02991-8

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    2017-06-05 kane35

    这样的手术应该考虑少做,愈合不好,保守治疗。

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Sun Jun 04 19:23:23 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206296, encodeId=888e206296e7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Jun 04 08:01:53 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206251, encodeId=bbfe206251e6, content=学习了增加知识了分享了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Jun 04 07:33:12 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206060, encodeId=5048206060fb, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jun 03 17:10:38 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206006, encodeId=dea22060068e, content=很好的文章,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-05 jeanqiuqiu
  5. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-04 luominglian113

    学习了,谢谢分享

    0

  6. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-04 laoli

    谢谢分享,学习了!

    0

  7. 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level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Jun 04 07:33:12 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206060, encodeId=5048206060fb, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jun 03 17:10:38 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206006, encodeId=dea22060068e, content=很好的文章,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-04 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1986558, encodeId=62be1986558c1, content=<a href='/topic/show?id=5822325417e' target=_blank style='color:#2F92EE;'>#前列腺癌根治术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32541, encryptionId=5822325417e, topicName=前列腺癌根治术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=bugit, createdTime=Sun Nov 19 04:30:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206764, encodeId=49c4206e64bd, content=这样的手术应该考虑少做,愈合不好,保守治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCxzIqGgHGpnv0v7a7MZQHVVjxvBfHWenpTPmFhDxa6vn3qno88vft2DRqYcyUBQFCRouANp2WgxQ/0, createdBy=b35a44222, 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Sun Jun 04 19:23:23 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206296, encodeId=888e206296e7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Jun 04 08:01:53 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206251, encodeId=bbfe206251e6, content=学习了增加知识了分享了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Jun 04 07:33:12 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206060, encodeId=5048206060fb, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jun 03 17:10:38 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206006, encodeId=dea22060068e, content=很好的文章,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-04 大爰

    学习了增加知识了分享了谢谢

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Sun Jun 04 19:23:23 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206296, encodeId=888e206296e7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Jun 04 08:01:53 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206251, encodeId=bbfe206251e6, content=学习了增加知识了分享了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Jun 04 07:33:12 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206060, encodeId=5048206060fb, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jun 03 17:10:38 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206006, encodeId=dea22060068e, content=很好的文章,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-03 dhzzm

    学习了分享了

    0

  10. 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level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Jun 04 07:33:12 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206060, encodeId=5048206060fb, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jun 03 17:10:38 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206006, encodeId=dea22060068e, content=很好的文章,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Jun 03 12:59:14 CST 2017, time=2017-06-03, status=1, ipAttribution=)]
    2017-06-03 清风拂面

    很好的文章,谢谢分享

    0

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淋巴结转移中的外软组织转移通过淋巴结囊进入淋巴结脂肪组织,从而参与了肿瘤细胞的扩张。最近,这个形态特性表明可以作为各种癌症类型的重要预后因子,但是它在前列腺癌中的角色仍旧不清楚。最近,有研究人员鉴定了其在前列腺癌中的角色,并首次进行了前列腺组织的元分析,并与外科手术治疗的预后参数、淋巴结阳性前列腺病人包括ENE+和ENE-进行了比较。研究人员利用风险比(RRs)来总结死亡或者复发数,并利用危险比(

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Y-box蛋白(YB-1)是一个RNA和DNA结合因子并且可以作为潜在的癌症预后因子。最近,研究人员为了评估YB-1的临床影响,在11152名前列腺癌病例中利用免疫组化技术进行了组织微阵列分析,并对细胞质和细胞核染色进行了分开的研究。研究发现,在正常上皮细胞中,细胞质YB-1没有或者很少,而在86.3%肿瘤细胞中发现。在肿瘤中,细胞质染色弱的、中等的和强的分别占29.6%、43.7%和13.0%,