Lancet:瑞士日内瓦新冠肺炎血清学阳性感染率研究

2020-06-13 MedSci原创 MedSci原创

尽管瑞士日内瓦50万人口中,2.5个月内报告了5000例新冠肺炎病例,但在这一波大流行期间,日内瓦大部分人口仍然未受感染。与10-64岁人群相比,5-9岁儿童和65岁以上人群的血清阳性率显著降低

血清抗体检测发现严重急性呼吸综合征冠状病毒2(anti-SARS-CoV-2)无症状感染者的重要方法,近日研究人员评估了疫情期间瑞士日内瓦人口中抗SARS-CoV-2抗体流行率变化。
 
SEROCoV-POP研究是一项以人群为基础的研究,在先前人口代表性调查中随机选取参与者及其5岁及以上的家庭成员进行一系列连续12周的血清调查。使用ELISA检测每个参与者的抗SARS-CoV-2-IgG抗体,估计血清流行率。
 
2020年4月6日至5月9日期间,研究人员从1339个家庭中招募了2766名参与者,其人口分布与日内瓦州相似。在第一周,研究人员估计血清阳性率为4.8%(n=341)。第二周估计为8.5%(n=469),第三周为10.9%(n=577),第四周为6.6%(n=604),第五周为10.8%(n=775)。5-9岁(相对危险度[RR]:0.32)和65岁以上(RR:0.50)人群的血清阳性风险显著低于20-49岁的人。考虑到血清转化时间,研究人员估计每报告一例确诊病例,社区中就有11.6例感染。
 
尽管瑞士日内瓦50万人口中,2.5个月内报告了5000例新冠肺炎病例,但在这一波大流行期间,日内瓦大部分人口仍然未受感染。与10-64岁人群相比,5-9岁儿童和65岁以上人群的血清阳性率显著降低。
 
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    2021-03-28 Tamikia
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    2020-12-31 howi
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    2020-06-13 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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    2020-06-13 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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