Clin Gastroenterology H:炎性肠病患者出院后60天内急性静脉血栓栓塞风险**

2020-05-01 MedSci原创 MedSci原创

患有炎症性肠病(IBD)的患者发生静脉血栓栓塞(VTE)的风险很高。本项研究评估了IBD患者中与再次入院出现VTE的时机和危险因素。

背景与目标: 患有炎症性肠病(IBD)的患者发生静脉血栓栓塞(VTE)的风险很高。本项研究评估了IBD患者中与再次入院出现VTE的时机和危险因素。

方法: 研究人员从全国再入院数据库中收集了有关IBD指数入院的数据,从2010年到2014年,该数据导致60天内再次入院接受VTE。研究人员使用单变量和多变量回归评估了未经调整的风险比(RR)与VTE再入相关的危险因素并调整了RR(aRR)作为效果指标。VTE再入院的时间间隔为10天,最多90天。

结果: 本项研究共确定了872122例IBD患者。超过90%的再入院发生在入院后的60天内。与VTE入院有关的因素包括既往VTE,住院时间更长,合并症,入院时采用柔性乙状结肠镜或结肠镜检查以及年龄大于18岁。其他危险因素包括入院时难辨梭状芽胞杆菌感染(aRR,1.47; 95%CI,1.17-1.55)和出院到熟练的护理机构或中间护理机构(aRR,1.39; 95%CI,1.14-1.70)或出院时家庭健康服务(aRR,1.65; 95%CI,1.41-1.94)。

结论: 在因IBD入院的患者中,大多数VTE再入院发生在出院后60天内。VTE的再入院与艰难梭菌感染有关,并流向熟练的护理机构,中级护理机构或家庭保健服务。

原始出处:

Adam S. Faye. Et al. Acute Venous Thromboembolism Risk Highest Within 60 Days After Discharge From the Hospital in Patients With Inflammatory Bowel Diseases. Clin Gastroenterology H.2020.

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    2020-12-19 fusion
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    2020-10-03 许安
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    2020-05-08 xue8602
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