JAHA:人种和社会经济状况独立影响外周动脉疾病患者的截肢风险!

2018-01-12 xing.T MedSci原创

由此可见,在同一SES阶层的黑人与白种人相比截肢风险显著增加,并且在控制合并症、就诊时PAD严重程度和使用药物后,黑人人种对肢体损失具有独立的影响。

黑人已被证明是外周动脉疾病(PAD)患者截肢的危险因素;然而,种族被认为是社会经济地位(SES)的一个标志,而不是真正的差距。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究的目的是探究种族和SES对PAD患者截肢风险的影响。

研究人员从全国退伍军人事务数据库中确定了2003年至2014年期间的PAD患者(n=155647)。暴露因素为种族和SES(通过住宅邮政编码测量地区的收入中位数)。该研究的主要结局为重大截肢事件。

黑人退伍军人更可能居住在低SES的社区以及发展为晚期PAD。与白人患者相比,每个SES阶层的黑人患者截肢风险较高。在Cox模型(调整变量)中,黑人相比于白人截肢风险高出37%(风险比为1.37;95%可信区间为1.30-1.45),而低SES是截肢风险增加的独立预测因子(风险比为1.12;95%可信区间为1.06-1.17),并且没有证据表明与种族存在相互作用。在预测的截肢风险分析中,不论PAD表现如何,黑人和低SES仍然是截肢的重要危险因素。

由此可见,在同一SES阶层的黑人与白种人相比截肢风险显著增加,并且在控制合并症、就诊时PAD严重程度和使用药物后,黑人人种对肢体损失具有独立的影响。

原始出处:


Shipra Arya, et al. Race and Socioeconomic Status Independently Affect Risk of Major Amputation in Peripheral Artery Disease.JAHA.2018. https://doi.org/10.1161/JAHA.117.007425

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  5. 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createdName=戒馋,懒,贪, createdTime=Fri Jan 12 21:32:54 CST 2018, time=2018-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277913, encodeId=70dc2e79136e, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Fri Jan 12 19:54:13 CST 2018, time=2018-01-12, status=1, ipAttribution=)]
    2018-01-14 zhaohui6731
  6. 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  7. 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createdName=戒馋,懒,贪, createdTime=Fri Jan 12 21:32:54 CST 2018, time=2018-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277913, encodeId=70dc2e79136e, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Fri Jan 12 19:54:13 CST 2018, time=2018-01-12, status=1, ipAttribution=)]
  8. 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  9. 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createdName=戒馋,懒,贪, createdTime=Fri Jan 12 21:32:54 CST 2018, time=2018-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277913, encodeId=70dc2e79136e, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Fri Jan 12 19:54:13 CST 2018, time=2018-01-12, status=1, ipAttribution=)]
    2018-01-12 戒馋,懒,贪

    谢谢分享学习了

    0

  10. 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    2018-01-12 sunfeifeiyang

    0

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