Diabetic Med:2型糖尿病患者久坐时间中断频率与空腹血糖,黎明现象和夜间血糖之间的剂量反应

2019-05-07 不详 网络

<span style="font-size:9.0pt;font-family:宋体;mso-ascii-theme-font:major-fareast; mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:major-fareast; color:black;mso-bidi-font-weight:bold">近日,国际杂

近日,国际杂志 《Diabetic Med》上在线发表一项关于2糖尿病患者久坐中断频率与空腹血糖,黎明现象和夜间血糖之间的剂量反应的研究。

探讨2糖尿病患者久坐中断频率与基础葡萄糖(空腹血糖,黎明现象和夜间血糖)之间的剂量反应。

在随机三种治疗中,两种平衡不完全阻滞试验中,122糖尿病患者(年龄60.0±3.2; BMI30.2±1.4 kg / m 2)完成了三个条件中的两个:坐着7小时每隔60分钟中断(条件1),30分钟(条件2)和15分钟(条件3)(通过3分钟的低强度步行休息)。activPAL3FreeStyle Libre用于评估身体活动/久坐行为和连续葡萄糖谱。提供标准化膳食,并计算治疗条件之前和之后的夜晚和清晨的基础葡萄糖的变化(平均值±SE)。

治疗条件后,条件3-1.0±0.2 mmol / lP <0.02; -3.1±1.3 hP = 0.004)与条件1-0.1±0.2 mmol/ l; 1.9±1.2h)相比,空腹血糖较低和黎明现象持续时间较短。与条件20.6±0.3 mmol/l)相比,条件3-0.6±0.4 mmol /lP = 0.041)的黎明现象的幅度减小。相对于条件26.1±4.8%,P <0.03)和条件12.5±1.8%,P = 0.02),条件3-9.7±3.9%)的夜间血糖变异性(变异系数)降低。夜间平均葡萄糖没有变化。

长时间坐着期间经常中断,每15分钟进行3分钟的低强度步行休息,可以改善空腹血糖,黎明现象和夜间血糖变异性,这可能是一种简单的治疗干预措施能改善血糖控制。

原始出处:

A. C. PaingK. A. McMillanA. F. Kirket al. Doseresponse between frequency of interruption of sedentary time and fasting glucose, the dawn phenomenon and nighttime glucose in Type 2 diabetes

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    2019-05-07 misszhang

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