JAHA:吸烟与血压之间的纵向关联

2021-04-28 MedSci原创 MedSci原创

尽管吸烟与BP改变之间的相关性很小,但在吸烟者中观察到的较高的PP可能部分导致该人群较高的心血管疾病风险,因为PP是中年后心血管疾病风险的强力预测指标。

慢性吸烟与血压(BP)之间的相关性仍未明确。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,黑人吸烟者的尼古丁代谢速​率比白人吸烟者要慢,种族差异导致黑人吸烟者对尼古丁的依赖以及血压升高。

研究人员使用重复回归模型对CARDIA(年轻成人冠状动脉风险发展)研究中4786名黑人和白人吸烟与收缩压、舒张压和脉压(PP)的纵向变化(30年)之间的相关性进行分析。

与不吸烟的黑人相比,吸烟黑人的收缩压和舒张血压均无差异,尽管吸烟黑人的PP高于不吸烟黑人(β=1.01 mmHg,P=0.028)。与不吸烟的白人相比,吸烟白人的收缩压相似,舒张压较低(β=-2.27 mmHg,P<0.001),PP较高(β=1.59 mmHg,P<0.001)。与从未吸烟者相比,长期戒烟的黑人或白人收缩压、舒张压或PP没有显著差异(所有P>0.05)。

由此可见,尽管吸烟与BP改变之间的相关性很小,但在吸烟者中观察到的较高的PP可能部分导致该人群较高的心血管疾病风险,因为PP是中年后心血管疾病风险的强力预测指标

原始出处:

Rachel E. Luehrs.et al.Cigarette Smoking and Longitudinal Associations With Blood Pressure: The CARDIA Study.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.019566

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    2021-04-29 zhaohui6731
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    2021-04-28 skywalk3004

    学习

    0

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    2021-04-28 学医无涯

    戒烟很重要

    0

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    2021-04-28 付彬

    好好看

    0

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