食用色素可有效治疗恶性脑肿瘤?

2016-02-29 佚名 新华社

29日日本研究人员日前宣布,通过动物实验发现一种红色的食用色素对治疗恶性胶质瘤有效,今后有望在此基础上开发出新的治疗药物。 胶质瘤是大脑肿瘤中的一种,对恶性胶质瘤的治疗非常棘手,通过外科手术很难完全清除患部,还需要配合使用药物,不过现有药物效果还不理想,因此需要开发更好的药物。 日本基础生物学研究所等机构研究人员在新一期英国《科学报告》杂志上报告说,由于已知恶性胶质瘤细胞内有一种名为PTPRZ

29日日本研究人员日前宣布,通过动物实验发现一种红色的食用色素对治疗恶性胶质瘤有效,今后有望在此基础上开发出新的治疗药物。

胶质瘤是大脑肿瘤中的一种,对恶性胶质瘤的治疗非常棘手,通过外科手术很难完全清除患部,还需要配合使用药物,不过现有药物效果还不理想,因此需要开发更好的药物。

日本基础生物学研究所等机构研究人员在新一期英国《科学报告》杂志上报告说,由于已知恶性胶质瘤细胞内有一种名为PTPRZ的酶会加剧癌变,他 们在约2.6万种化合物中寻找能抑制这种酶的物质,结果发现一种名为SCB4380的低分子化合物有效。这种化合物在日本是作为食品和化妆品中的红色素使用。

直接使用这种物质无法通过恶性胶质瘤的细胞膜,但研究人员发现利用一种脂质体包裹这种色素就可以克服这个问题。研究人员对16只脑内有恶性胶质 瘤的大鼠进行了实验,将用脂质体包裹的色素注射到它们大脑内,结果发现7周后肿瘤体积缩小,仅有未注射色素对照组大鼠肿瘤体积的一半左右。

研究人员表示,今后将在此基础上继续开展研究,争取开发出能有效治疗恶性胶质瘤的新型药物。

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    2016-09-21 sunylz
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    2016-03-01 破风4392

    这个有戏了

    0

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    2016-03-01 1ddeb060m96(暂无匿称)

    对大鼠效果还挺明显的

    0