JAMA Pediatrics:早产儿或低出生体重与成年后智商有关

2021-06-01 MedSci原创 MedSci原创

尽管极早产儿相对较少,占全世界所有早产儿的5.2%。据数据显示,这些不成熟的婴儿患各种并发症风险升高,包括支气管肺发育不良,脑出血,坏死性小肠结肠炎,败血症和视网膜病变等,且与长期不良结果相关。

尽管极早产儿相对较少,占全世界所有早产儿的5.2%。据数据显示,这些不成熟的婴儿患各种并发症风险升高,包括支气管肺发育不良,脑出血,坏死性小肠结肠炎,败血症和视网膜病变等,且与长期不良结果相关。极早产儿与全世界医疗保健系统的沉重负担有关。

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妊娠少于28周的婴儿定义为极早产儿(VPT),出生体重低于 1.5千克定义为极低出生体重产儿(VLBW)。有研究显示,那些VPT/VLBW儿童期的认知能力较低。然而,很少有关于VPT/VLBW在成年期与智力发育相关的研究。

近日,发表在JAMA Pediatrics杂志的一项研究显示,VPT/VLBW与成年期后智商低下有关。

在这项研究中,研究人员检索了PubMed 已发布的相关数据和来自 2项目欧洲儿童和成人早产儿研究 RECAP)和成人早产儿国际合作研究(APIC)的数据进行荟萃分析。所收集的研究包括前瞻性纵向队列研究,这些研究评估了 VPT / VLBW 出生的成年人的智商(n=1068),由足月出生的成年人组成的对照组(n= 1067 )。

结果显示,一般人群的平均智商得分为 100。与足月出生的成年人(出生 37-41 周)相比,VPT/VLBW 个体的智商得分大约为88即使是排除了有神经感觉障碍或学习障碍,VPT/VLBW与足月出生成人之间的智商仍然相差9.8 个智商点。 VPT/VLBW 参与者中,新生儿严重的肺部问题、新生儿脑出血以及母亲受教育程度较低都与与成年期较低的智商分数显著相关。

研究人员表示,虽然大多数 VPT/VLBW的认知发展在正常范围内,但绝大多数可能受益于早期制定的新生儿护理干预措施,包括减少支气管肺发育不良,脑出血等。

原始出处

Robert Eves et al, Association of Very Preterm Birth or Very Low Birth Weight With Intelligence in Adulthood, JAMA Pediatrics (2021). DOI: 10.1001/jamapediatrics.2021.1058

 

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    2022-03-04 feather89
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    2022-02-12 hbwxf
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    2021-06-03 晓辰
  5. [GetPortalCommentsPageByObjectIdResponse(id=1728959, encodeId=b4cc1e28959a7, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Mar 04 00:18:01 CST 2022, time=2022-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639774, encodeId=b7021639e74ae, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jan 15 01:18:01 CST 2022, time=2022-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958557, encodeId=f13d195855e52, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Feb 12 02:18:01 CST 2022, time=2022-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323017, encodeId=0508132301ec3, content=<a href='/topic/show?id=a38660034ac' target=_blank style='color:#2F92EE;'>#智商#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60034, encryptionId=a38660034ac, topicName=智商)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Thu Jun 03 13:18:01 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440770, encodeId=40a61440e7009, content=<a href='/topic/show?id=f99e3142e4d' target=_blank style='color:#2F92EE;'>#出生体重#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31427, encryptionId=f99e3142e4d, topicName=出生体重)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5ffd4758992, createdName=ms9608593228839890, createdTime=Thu Jun 03 13:18:01 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571491, encodeId=c29115e1491be, content=<a href='/topic/show?id=d13c26153fd' target=_blank style='color:#2F92EE;'>#低出生体重#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26153, encryptionId=d13c26153fd, topicName=低出生体重)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5e7915741670, createdName=linne325, createdTime=Thu Jun 03 13:18:01 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036648, encodeId=bb3610366482c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Wed Jun 02 01:18:01 CST 2021, time=2021-06-02, status=1, ipAttribution=)]
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1728959, encodeId=b4cc1e28959a7, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Mar 04 00:18:01 CST 2022, time=2022-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639774, encodeId=b7021639e74ae, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jan 15 01:18:01 CST 2022, time=2022-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958557, encodeId=f13d195855e52, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Feb 12 02:18:01 CST 2022, time=2022-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323017, encodeId=0508132301ec3, content=<a href='/topic/show?id=a38660034ac' target=_blank style='color:#2F92EE;'>#智商#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60034, encryptionId=a38660034ac, topicName=智商)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Thu Jun 03 13:18:01 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440770, encodeId=40a61440e7009, content=<a href='/topic/show?id=f99e3142e4d' target=_blank style='color:#2F92EE;'>#出生体重#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31427, encryptionId=f99e3142e4d, topicName=出生体重)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5ffd4758992, createdName=ms9608593228839890, createdTime=Thu Jun 03 13:18:01 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571491, encodeId=c29115e1491be, content=<a href='/topic/show?id=d13c26153fd' target=_blank style='color:#2F92EE;'>#低出生体重#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26153, encryptionId=d13c26153fd, topicName=低出生体重)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5e7915741670, createdName=linne325, createdTime=Thu Jun 03 13:18:01 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036648, encodeId=bb3610366482c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Wed Jun 02 01:18:01 CST 2021, time=2021-06-02, status=1, ipAttribution=)]
    2021-06-02 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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