JACC:冠脉剪切应力可以预测冠心病患者的心梗风险

2018-10-12 MedSci MedSci原创

冠脉损伤伴低节段性流量储备(FFR)与更高的血管再生率相关,高壁剪切应力(WSS)与斑块易损性增加有关。本研究的目的旨在评估稳定性冠心病(CAD)患者的WSS与心梗发生的相关性。在FAME II临床研究的FFR ≤0.80的441例患者中,34例(8%)患者在3年内发生了心梗。29例发生血管相关性心梗且有适合三维重建的血管造影照片的患者与29例无心梗的对照进行了匹配分析。这58例患者的平均年龄为6

冠脉损伤伴低节段性流量储备(FFR)与更高的血管再生率相关,高壁剪切应力(WSS)与斑块易损性增加有关。本研究的目的旨在评估稳定性冠心病(CAD)患者的WSS与心梗发生的相关性。

在FAME II临床研究的FFR ≤0.80的441例患者中,34例(8%)患者在3年内发生了心梗。29例发生血管相关性心梗且有适合三维重建的血管造影照片的患者与29例无心梗的对照进行了匹配分析。这58例患者的平均年龄为62岁,46例(79%)为男性,边际Cox模型分析结果显示低的FFR和高的冠脉近端WSS可以预测心梗的发生。联合冠脉近端WSS和FFR可以大大提高预测心梗的概率。

研究结果显示,在稳定性冠心病伴血流动力学损伤的患者中,冠脉近端的高壁剪切应力可以预测心梗的发生,联合节段性流量储备可以提高预测价值。

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    2019-04-22 hbwxf
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    2018-10-12 flysky120

    冠心病与心梗的风险

    0

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    2018-10-12 lietome15

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

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