J Bone Jt Infect:采用肢体救治重建术治疗胫骨和踝关节慢性骨髓炎

2020-12-03 MedSci原创 MedSci原创

本研究旨在确定我院肢体抢救治疗方案的成功性,并确定胫踝慢性骨髓炎患者肢体抢救技术成功与失败的预测因素,研究结果已在线发表于J Bone Jt Infect。

本研究旨在确定我院肢体抢救治疗方案的成功性,并确定胫踝慢性骨髓炎患者肢体抢救技术成功与失败的预测因素,研究结果已在线发表于J Bone Jt Infect

采用回顾性研究设计,分析胫骨或踝关节慢性骨髓炎患者接受肢体抢救技术的因素和结果。主要结果测量包括感染得到控制,不需要截肢或慢性抗生素抑制,以及无感染的发生。

 

平均随访时间为3. 9年。在接受慢性骨髓炎治疗的67名患者(平均年龄:51.4岁)中,有54名患者出现了骨不联合。61名患者(91.0%)通过肢体抢救控制了感染。5例最终需要截肢,1例仍需每日服用抗生素。糖尿病患者并发神经病变和肢体抢救手术次数增多,与明显增高的失败率相关。54名患者中,有48名(88.9%)非关节骨感染者也成功愈合。糖尿病和需要更多的肢体抢救手术,失败率也明显较高。

综上所述,该结果表明,肢体抢救术是慢性骨髓炎和下肢感染性非关节炎患者有效的治疗方法。糖尿病神经病变是阻碍骨成功愈合的危险因素。

 

原始出处:

 

Aaron LamShawn S Richardson, et al., Chronic Osteomyelitis of the tibia and ankle treated with Limb Salvage Reconstruction. J Bone Jt Infect . 2019 Dec 10;4(6):306-313. doi: 10.7150/jbji.40337. eCollection 2019.

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    2021-03-17 apoenzyme
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    2020-12-05 宋威
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    2020-12-05 yb6561
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    2020-12-05 qilu_qi

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