Ann Rheum Dis:未生育、产后早期和晚期女性骶髂关节骨髓水肿的患病率

2020-06-13 xiangting MedSci原创

EPP组SIJ的BME患病率高于NP。与LPP相比,EPP的BME患病率更高,并且BME随着分娩时间的延长而减少。

这项研究旨在确定产后早期(EPP)、未生育(NP)和产后晚期(LPP)女性骶髂关节(SIJ)骨髓水肿(BME)的患病率,并确定与SIJ出现BME相关的因素。

有三组参与者:NP(未生育)、EPP(12个月内分娩)和LPP(分娩超过24个月)。主要结局是SIJ MRI上存在BME和/或结构性病变(糜烂、骨赘、强直和硬化)。

EPP(33%)组BME患病率高于NP(14%,p=0.001),但与LPP(21%,p=0.071)没有区别。EPP、NP和LPP组中伴BME女性的国际脊椎关节炎评估协会(ASAS)骶髂关节炎MRI标准阳性率分别为75%、71%和80%。EPP(38%)组硬化的患病率与LPP(28%,p=0.135)相似,但高于NP(18%,p=0.001)。最后,尽管LPP与NP之间存在差异(p=0.006),但EPP(28%)的骨赘患病率与LPP(42%)和NP(27%)相似。

EPP组SIJ的BME患病率高于NP。与LPP相比,EPP的BME患病率更高,并且BME随着分娩时间的延长而减少。SIJ有BME的女性中,四分之三ASAS 骶髂关节炎MRI标准阳性,表明将存在BME作为阳性诊断的主要标准可以导致假阳性结果。SIJ MRI不应单独进行解释,因为年龄、分娩时间和其他因素可能会超过MRI结果的相关性。

原始出处:

Adel Hoballah. MRI of sacroiliac joints for the diagnosis of axial SpA: prevalence of inflammatory and structural lesions in nulliparous, early postpartum and late postpartum women. Ann Rheum Dis. June 2020.

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    2020-06-15 小华子
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