Circulation:公众应用除颤对院外心脏骤停后生存率的影响

2017-07-09 xiangting MedSci原创

这项系统综述显示,PAD治疗的OHCA患者的中位总生存率为40%。

尽管最近的进展,院外心脏骤停(OHCA)后的平均存活率仍低于10%。自动外部除颤器(AED)的早期除颤是OHCA患者最重要的干预措施,其生存率高于50%。因此,国际指南建议将AEDs作为公众应用除颤方案(PAD)的一部分放置到社区。但是,提出了如何准确地增加和利用公共可用AED的不同策略。这篇系统综述旨在评估PAD和不同PAD策略对OHCA后存活率的影响。

在2015年8月31日,系统地对Pubmed、Embase和Cochrane图书馆进行了检索,查找关于使用AED作为非紧急医疗服务的OHCA患者出院生存情况的观察性研究。根据应用除颤器的人员,将PAD分为三组:非指定的第一反应人员,紧急医疗调度中心(EMDC)派遣的专业第一反应人员(消防员/警察)或由EMDC派遣的第一反应人员。

共纳入41项研究,18项是名非指定的第一反应人员使用PAD,20项是EMDC派遣专业第一反应人员(消防员/警察)报告了PAD,另有3项两者都有。没有发现合格的由EMDC派遣第一反应者PAD后的生存报道。OHCA使用PAD后出院时的整体生存率中位数为40.0%(范围9.1-83.3)。非派遣的第一反应者的除颤与最高生存率相关,中位数为53.0%(范围26.0-72.0),EMDC派遣专业第一反应人(消防员/警察)的除颤与中位生存率相关(28.6%)(范围9.0-76.0)。由于纳入研究的异质性较大,不能进行不同生存结果的荟萃分析。

这项系统综述显示,PAD治疗的OHCA患者的中位总生存率为40%。与EMDC派遣的专业第一反应者相比,非指定的第一反应者的除颤被发现与对生存率最高相关。EMDC派遣第一反应人进行PAD可能是一个有希望的方式,但缺乏证据。

原始出处:

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    2017-07-11 zhouqu_8
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    2017-07-10 天地飞扬

    谢谢分享

    0

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    2017-07-09 130****4638

    学习了谢谢分享

    0

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    2017-07-09 为你把脉

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