Sci Rep:利用二维和三维超声进行尿道下裂产前诊断分析

2019-06-25 AlexYang MedSci原创

最近,有研究人员比较了尿道下裂患者的2维超声成像(2DUS)与3维超声成像(3DUS)组合和2DUS单独使用时,在产前诊断中的表现以及超声细节方面的表现情况。研究总共包括了47名胎儿,之后,研究人员利用2DUS和3DUS进行成像。研究人员获得了产后的跟踪调查数据,并确认了28个案例为尿道下裂。研究发现,与单独的2DUS相比,2DUS组合3DUS成像倾向于具有更高的AUC(0.85 vs. 0.76

最近,有研究人员比较了尿道下裂患者的2维超声成像(2DUS)与3维超声成像(3DUS)组合和2DUS单独使用时,在产前诊断中的表现以及超声细节方面的表现情况。

研究总共包括了47名胎儿,之后,研究人员利用2DUS和3DUS进行成像。研究人员获得了产后的跟踪调查数据,并确认了28个案例为尿道下裂。研究发现,与单独的2DUS相比,2DUS组合3DUS成像倾向于具有更高的AUC(0.85 vs. 0.76; p=0.08)、ACC(85.1 vs. 76.6%; p=0.22)、SEN(85.7 vs. 78.6%; p=0.63)和SPE(84.2 vs. 73.7%; p=0.50),但是差异并不显著。两种方法的一致度适中(kappa=0.592),并且都展现了精确的短阴茎和钝头阴茎形态。另外,2DUS组合3DUS成像还能够显示出其他的一些特性,比如阴茎下弯、不完整的包皮等。

最后,研究人员指出,2DUS组合3DUS成像表现出了比2DUS更好的表现能力,尽管差异并不显著。在诊断胎儿尿道下裂中,3DUS是2DUS的非常有用的互补手段,并且能够为诊断和预后提供更多的信息。

原始出处:

Xiaohua Li, Aqing Liu, Zhonglu Zhang et al. Prenatal diagnosis of hypospadias with 2-dimensional and 3-dimensional ultrasonography. Sci Rep. 17 Jun 2019

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    2020-04-22 lifestar
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    2019-06-27 qilu_qi
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