Diabetic Med:低维生素D水平不是2型糖尿病患者抑郁症患病率升高的因素?

2017-07-06 MedSci MedSci原创

近日,国际杂志 《Diabetic medicine》上在线发表一项关于低维生素D水平不是2型糖尿病患者抑郁症患病率升高的因素的霍恩研究,评估低血清25-羟维生素D水平是否能解释2型糖尿病患者更高的抑郁症患病率。

近日,国际杂志 《Diabetic medicine》上在线发表一项关于低维生素D水平不是2糖尿病患者抑郁症患病率升高的因素的霍恩研究,评估低血清25-羟维生素D水平是否能解释2糖尿病患者更高的抑郁症患病率。

研究人员对参加了人群的队列研究的527人(60-87岁)的进行横断面分析。根据2006年世卫组织的标准, 对2糖尿病进行定义,葡萄糖耐量减低,空腹血糖和正常葡萄糖耐量受损。流行病学抑郁症研究中心问卷调查使用≥16的临界分数来确定抑郁相关临床症状。

Logistic回归分析证实,与正常葡萄糖耐量相比,葡萄糖耐量异常/空腹血糖异常的女性患者和2型糖尿病患者确实有较高的抑郁症状风险[未调整的优势比3.6695CI 1.598.43)和3.0495CI 1.575.88 )。血清25-羟基维生素D水平不是葡萄糖耐量异常/空腹血糖异常或2型糖尿病和抑郁症状之间的关联的介导因素[非标准间接作用0.00195CI -0.0630.079)和0.00495CI- 0.0250.094)。

研究发现没有证据表明低维生素D水平是造成2型糖尿病患者抑郁症得分升高的因素。

原始出处:

S. Westra, S. Simsek, F. Rutters,et al. Low vitamin D levels are not a contributing factor to higher prevalence of depressive symptoms in people with Type 2 diabetes mellitus: the Hoorn study

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    2017-07-06 天涯183

    非常好的文章,学习了,很受益

    0

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