Clinica Chimica Acta:经皮冠状动脉介入治疗急性ST段抬高性心肌梗死患者术前纤维蛋白原-白蛋白比值对死亡率的影响

2019-08-06 不详 MedSci原创

研究了基于炎症和血液流变学改变的急性<span lang="EN-US" style="font-size:12.0pt;mso-bidi-font-size:14.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;; mso-fareast-font-family:宋体;mso-bidi-font-family:&quot;Ti

研究了基于炎症和血液流变学改变的急性ST段抬高心肌梗死STEMI)患者的纤维蛋白原 - 白蛋白比值(FAR)的预后价值,并确定FAR是否可以作为预测急性冠状动脉事件信息的全球注册(GRACE)评分的补充增量预测信息。

研究人员回顾性分析了475例接受pPCI治疗的STEMI患者。采用Kaplan-Meier曲线、Cox比例危险回归模型、Hosmer-Lemeshow检验评价FAR对患者的预后价值。

根据0.080的最佳截断值,将患者分为高FAR(0.080)和低FAR(<0.080)。研究结果显示,总共有59名患者(12.4%)死亡; FAR患者的死亡率高于低FAR患者(20.5vs8.6%,p <.001)。 FARC反应蛋白,GRACE评分和Gensini评分呈正相关(p <.001)。 在多变量分析中,FAR是接受pPCISTEMI患者的独立预后因素。

研究表明,术前FAR是进行pPCISTEMI患者的一个独立预后因素,可能改善STEMI的风险分层。

原始出处:

LeiXiaoYuJiaThe impact of preoperative fibrinogen-albumin ratio on mortality in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

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    2019-08-11 windight
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    2019-08-08 珙桐
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    2019-08-08 gdsun
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    2019-08-08 hyf035

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