Am J Clin Nutr:孕前坚持植物性饮食可降低妊娠期糖尿病风险

2021-10-02 Nebula MedSci原创

约 4-9% 的孕妇会经历妊娠期糖尿病(GDM)。新的证据表明植物性饮食对一般健康个体的糖代谢可产生有益影响。但是,坚持植物性饮食是否会降低 GDM 的风险尚不明确。

约 4-9% 的孕妇会经历妊娠期糖尿病(GDM)。新的证据表明植物性饮食对一般健康个体的糖代谢可产生有益影响。但是,坚持植物性饮食是否会降低 GDM 的风险尚不明确。

注:植物性饮食是指以植物性食物为基础,不含动物性食物,或只含有少量肉类的饮食,与纯素食不一样。

这是一项大型的前瞻性研究,旨在评估植物性饮食与 GDM 风险之间的相关性。

纳入了来自护士健康研究 II(1991-2001)的 14926 位报告了≥1 次单胎妊娠的且在索引妊娠前无 GDM 病史的女性。通过 FFQ 评估的总植物性饮食指数 (PDI)、健康植物性饮食指数 (hPDI) 和不健康植物性饮食指数 (uPDI) 来衡量孕前对植物性饮食的依从性。根据自我报告的医生诊断确定首次 GDM 事件,并审查医疗记录进行验证。

植物性饮食与GDM风险的相关性

在 10 年随访过程中,20707 次妊娠中共记录了 846 例 GDM。对 PDI 和 hPDI 的更高依从性与更低的 GDM 风险相关。根据 PDI,最高和最低五分位数相比(Q5 vs Q1)的多变量调整的相对风险(RR)为 0.70 (95% CI 0.56-0.87; p=0.0004),每增加 10 个点,RR 为 0.80 (0.71-0.90)。根据 hPDI,Q5 与 Q1 相比的 RR 为 0.75(95% CI 0.59-0.94; p=0.009),每增加 10 个点的 RR 为 0.86(0.77-0.95)。

根据孕前 BMI 进一步调整后,PDI 和 hPDI 与 GDM 的相对风险的相关性有所减弱,但仍具有显著性(PDI 和 hPDI 每增加 10 个点的相对风险都是 0.89)。最后,uPDI 与 GDM 风险无明显关联。

总而言之,该研究结果提示,孕前对健康的植物性饮食的依从性越好,GDM 风险就越低,但不健康的植物性饮食与 GDM 风险无关

原始出处:

Chen Zhangling,Qian Frank,Liu Gang et al. Prepregnancy plant-based diets and the risk of gestational diabetes mellitus: a prospective cohort study of 14,926 women.[J] .Am J Clin Nutr, 2021,https://doi.org/10.1093/ajcn/nqab275

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    2022-01-13 xuyong535
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    2021-12-01 szhvet
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    2021-10-04 wjcjjian
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1745384, encodeId=bcb71e453849d, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Thu Jan 13 16:22:55 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1659614, encodeId=e9cb165961481, content=<a href='/topic/show?id=c42845239ef' target=_blank style='color:#2F92EE;'>#孕前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45239, encryptionId=c42845239ef, topicName=孕前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c8925003801, createdName=szhvet, createdTime=Wed Dec 01 00:22:55 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251296, encodeId=8230125129696, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Mon Oct 04 02:22:55 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1253675, encodeId=df0a12536e558, content=<a href='/topic/show?id=9d5d44888a9' target=_blank style='color:#2F92EE;'>#妊娠期糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44888, encryptionId=9d5d44888a9, topicName=妊娠期糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Oct 04 02:22:55 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533284, encodeId=e054153328407, content=<a href='/topic/show?id=5aa662e4339' target=_blank style='color:#2F92EE;'>#植物性饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62743, encryptionId=5aa662e4339, topicName=植物性饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=24ef12409748, createdName=lingaifan, createdTime=Mon Oct 04 02:22:55 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1056941, encodeId=297a10569419c, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Sat Oct 02 12:42:10 CST 2021, time=2021-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1056935, encodeId=76a41056935d0, content=写的真不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b905623974, createdName=ms6000001338262315, createdTime=Sat Oct 02 11:44:41 CST 2021, time=2021-10-02, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1745384, encodeId=bcb71e453849d, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Thu Jan 13 16:22:55 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1659614, encodeId=e9cb165961481, content=<a href='/topic/show?id=c42845239ef' target=_blank style='color:#2F92EE;'>#孕前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45239, encryptionId=c42845239ef, topicName=孕前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c8925003801, createdName=szhvet, createdTime=Wed Dec 01 00:22:55 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251296, encodeId=8230125129696, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Mon Oct 04 02:22:55 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1253675, encodeId=df0a12536e558, content=<a href='/topic/show?id=9d5d44888a9' target=_blank style='color:#2F92EE;'>#妊娠期糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44888, encryptionId=9d5d44888a9, topicName=妊娠期糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Oct 04 02:22:55 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533284, encodeId=e054153328407, content=<a href='/topic/show?id=5aa662e4339' target=_blank style='color:#2F92EE;'>#植物性饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62743, encryptionId=5aa662e4339, topicName=植物性饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=24ef12409748, createdName=lingaifan, createdTime=Mon Oct 04 02:22:55 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1056941, encodeId=297a10569419c, content=已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Sat Oct 02 12:42:10 CST 2021, time=2021-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1056935, encodeId=76a41056935d0, content=写的真不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b905623974, createdName=ms6000001338262315, createdTime=Sat Oct 02 11:44:41 CST 2021, time=2021-10-02, status=1, ipAttribution=)]
    2021-10-02 ms5000000518166734

    已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读已读

    0

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    2021-10-02 ms6000001338262315

    写的真不错

    0

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