PLoS One:多不饱和脂肪酸对前列腺癌细胞的增殖和生存影响

2019-07-28 AlexYang MedSci原创

前列腺癌恶化到致死的阶段的标志是癌细胞不依赖激素增殖的出现。营养和流行病学研究表明了前列腺癌的恶化与多不饱和脂肪酸(PUFA)的摄入有关。最近,有研究人员为了阐明上述相关性在细胞水平的机制,他们在一个细胞增殖和生存试验中,比较了激素依赖和不依赖激素的前列腺癌细胞对添加了PUFAs的生长培养基的敏感性情况。他们的结果表明了激素依赖的细胞对各种类型的PUFAs相对不敏感,同时,不依赖激素的细胞的生长和

前列腺癌恶化到致死的阶段的标志是癌细胞不依赖激素增殖的出现。营养和流行病学研究表明了前列腺癌的恶化与多不饱和脂肪酸(PUFA)的摄入有关。

最近,有研究人员为了阐明上述相关性在细胞水平的机制,他们在一个细胞增殖和生存试验中,比较了激素依赖和不依赖激素的前列腺癌细胞对添加了PUFAs的生长培养基的敏感性情况。他们的结果表明了激素依赖的细胞对各种类型的PUFAs相对不敏感,同时,不依赖激素的细胞的生长和生存均受到PUFAs(n-3或者n-6)强烈的抑制。因此,研究人员推测上述差异至少可以部分的解释前列腺癌中特异饮食脂肪产生的影响。

最后,研究人员指出,他们的数据强调了日常饮食干预应该是新治疗方法的一部分,从而阻止前列腺癌的恶化。

原始出处:

Bratton BA, Maly IV, Hofmann WA et al. Effect of polyunsaturated fatty acids on proliferation and survival of prostate cancer cells. PLoS One. 17 Jul 2019

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (8)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
    2019-07-30 yxch36
  5. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1689368, encodeId=e3fe1689368f6, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7f928794244, createdName=12498ca5m92暂无昵称, createdTime=Fri Mar 20 11:18:00 CST 2020, time=2020-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790358, encodeId=1eeb1e9035873, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Apr 24 07:18:00 CST 2020, time=2020-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932146, encodeId=d1c419321465e, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Fri Jan 17 22:18:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252626, encodeId=55eb12526265d, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378723, encodeId=4eaa13e8723a7, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580000, encodeId=605a15800001f, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620259, encodeId=e34b1620259f8, content=<a href='/topic/show?id=c62132549a5' target=_blank style='color:#2F92EE;'>#前列腺癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32549, encryptionId=c62132549a5, topicName=前列腺癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e09820091072, createdName=lifestar, createdTime=Tue Jul 30 04:18:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040509, encodeId=5159104050925, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 28 16:18:00 CST 2019, time=2019-07-28, status=1, ipAttribution=)]
    2019-07-28 misszhang

    前列腺癌相关研究,学习了,谢谢梅斯

    0

相关资讯

BMC Cancer:脂肪酸结合蛋白7可能是透明细胞肾细胞癌的标记和治疗靶标

为了鉴定透明细胞肾细胞癌(ccRCC)中新的潜在的治疗靶标,最近,有研究人员进行了转录组分析。他们的研究展现了脂肪酸结合蛋白7(FABP7)在ccRCC中与正常肾脏相比,具有最高的均值差异化过表达。研究人员对40名晚期ccRCC案例进行了免疫组化染色,从而来调查临床病理参数与FABP7之间的相关性。该群体的年龄范围为40-83岁,男性有33名,其中22个案例为pT≥3,19个案例为M1,16个案例

J Lipid Research:科学家在多不饱和脂肪酸与代谢综合征发病风险研究中取得进展

根据英国曼彻斯特城市大学的一项研究,快餐、蛋糕和加工肉产品等促炎食物(高胆固醇、高饱和脂肪酸和高碳水化合物的食物)的饮食会使患抑郁风险上升40%。

PNAS:在去势难治性前列腺癌中,以雄激素受体信号为靶标的脂肪生成从头抑制研究

前列腺癌恶化的一个标志是通过脂肪酸合成酶(FASN)过表达而引起的脂肪代谢的异常调控。FASN是脂肪酸从头合成的一个关键酶。转移去势难治性前列腺癌(mCRPC)可以通过很多种机制发展为雄激素受体(AR)信号抑制剂的抗性情况,包括了AR变异体V7(AR-V7)的持续性激活。最近,有研究人员开发了一种FASN抑制剂(IPI-9119),并且阐释了选择性的FASN抑制剂能够通过代谢重组拮抗CRPC生长,

Nat Commun:研究发现蛋白质翻译后修饰通过泛素化降解途径调节脂肪酸合成的新机制

2月7日,国际学术期刊《自然-通讯》(Nature Communications)在线发表了中国科学院上海营养与健康研究所李于研究组的最新研究成果“Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene”。该研究发现腺苷酸活化蛋白激酶(AMPK)通

Invest Ophthalmol Vis Sci:脉络膜血症患者的循环细胞中不存在晶体和脂肪酸异常!

加拿大艾伯塔大学眼科学与视觉科学系的Radziwon A等人近日在Invest Ophthalmol Vis Sci发表了一篇文章,他们想确认脉络膜血症(CHM)是否是一种全身性疾病。

J Lipid Res:全新Meta分析称,改善血脂,葵花籽油和菜籽油优于橄榄油

近期发表在脂质研究杂志的一项最新Meta分析却发现,葵花籽油、油菜籽油等种子油优于橄榄油。