J Am Acad Dermatol:黑色素瘤自诊工具——ABCDE原则和丑小鸭征

2017-10-31 MedSci MedSci原创

背景:为了辨识黑色素瘤,ABCDE原则广泛应用于一般人群,其主要内容包括:A代表不对称,B代表边界不规则,C代表着色多样化,D代表直径>6 mm,E代表皮损渐进性隆起。而丑小鸭征(ugly duckling sign)也是黑色素瘤识别策略的替代标志,但并未被普遍使用。目的:在普通人群中比较丑小鸭征和ABCD原则辨识黑色素瘤的敏感性、特异性和准确性。方法:研究中,参与者被随机分组接受黑色素瘤自

背景:为了辨识黑色素瘤,ABCDE原则广泛应用于一般人群,其主要内容包括:A代表不对称,B代表边界不规则,C代表着色多样化,D代表直径>6 mm,E代表皮损渐进性隆起。

而丑小鸭征(ugly duckling sign)也是黑色素瘤识别策略的替代标志,但并未被普遍使用。

目的:在普通人群中比较丑小鸭征和ABCD原则辨识黑色素瘤的敏感性、特异性和准确性。

方法:研究中,参与者被随机分组接受黑色素瘤自诊教学,分为ABCD原则组和丑小鸭征组。然后根据分组给与相应的教学课程。随后参与者对9个病灶(7个痣和2个MM)的图像进行测试,他们需要将每个图像分为MM或非MM。

结果:ABCD原则组共有51名参与者,丑小鸭征组共有50名参与者。两组参与者对MM的识别敏感性相似。在丑小鸭征组,MM识别的特异性和准确性显著较高(P =0.02,P =0.02)。

局限性:研究未研究ABCDE原则中的“E”,即皮损渐进性隆起。没有对参与者的知识保留情况进行随访。

结论:丑小鸭征显著提高了黑色素瘤识别的精确度和特异性。研究人员建议,除了传统的ABCDE原则外,还应加丑小鸭征的普及教育。

原始出处:

Ilyas M, Costello CM,et al.The role of the ugly duckling sign in patient education.J Am Acad Dermatol. 2017 Sep 27. pii: S0190-9622(17)32054-6. doi: 10.1016/j.jaad.2017.06.152. [Epub ahead of print]

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    2018-09-13 lishizhe
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    2018-05-06 sunylz
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  5. 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  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Oct 31 19:21:12 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-11-01 llaq

    丑小鸭征

    0

  7. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Oct 31 19:21:12 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-11-01 wxl882001

    学习一下

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/C20CB8E4EBB36F5B821651C710BCB491/100, createdBy=18de1715848, createdName=lofter, createdTime=Wed Nov 01 07:36:02 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257566, encodeId=83c725e5666d, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Tue Oct 31 19:24:15 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257563, encodeId=67c925e563e6, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Oct 31 19:21:12 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-11-01 lofter

    学习了感谢分享

    0

  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Oct 31 19:21:12 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-10-31 131****1460

    学习了受益匪浅

    0

  10. 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    2017-10-31 orangesking

    0

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